Evidence map›Paper›PMID 31191822›Full record

ArticleOncotarget2019

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas.

Joshua Loewenstern, John Rutland, Corey Gill, Hanane Arib, Margaret Pain, Melissa Umphlett, Yayoi Kinoshita, Russell McBride, Michael Donovan, Robert Sebra and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. British journal of neurosurgery · 2025
    Article
  4. Article
  5. Role ofCancers · 2024
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Clinical, Histopathologic and Genetic Features of Rhabdoid Meningiomas.International journal of molecular sciences · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. SWI/SNF chromatin remodeling complex alterations in meningioma.Journal of cancer research and clinical oncology · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Joshua LoewensternDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
John RutlandDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Corey GillDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Hanane AribDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Margaret PainDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Melissa UmphlettDepartment of Pathology, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Yayoi KinoshitaDepartment of Pathology, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Russell McBrideDepartment of Pathology, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Michael DonovanDepartment of Pathology, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Robert SebraDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Joshua BedersonDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Mary FowkesDepartment of Pathology, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Raj ShrivastavaDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY, New York, USA.
Icahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A significant proportion of low-grade WHO grade I and higher-grade WHO grade II or III meningiomas are at risk to develop post-resection recurrence. Though recent studies investigated genomic alterations within histological subtypes of meningiomas, few have compared genomic profiles of primary meningiomas matched to their recurrences. The present study aimed to identify oncogenic driver mutations that may indicate risk of meningioma recurrence and aggressive clinical course. Seventeen patients treated for low-grade (

Indexed as

driver mutationgenomicsmeningiomaprogression-free survivaltumor recurrence

Identifiers

PMID31191822
PMCPMC6544407
OpenAlexW2953526441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.