Evidence map›Paper›PMID 31191756›Full record

ArticleDisease markers2019

A Prediction Rule for Overall Survival in Non-Small-Cell Lung Cancer Patients with a Pathological Tumor Size Less Than 30 mm.

Wang-Yu Zhu, Ke-Xin Fang, Jian-Ying He, Ri Cui, Yong-Kui Zhang, Han-Bo Le

Abstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wang-Yu ZhuCell and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang Province, China.ORCID 0000-0003-4805-0800
Ke-Xin FangCell and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang Province, China.ORCID 0000-0002-7207-0900
Jian-Ying HeCell and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang Province, China.
Ri CuiLung Cancer Research Center, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang Province, China.ORCID 0000-0001-6202-8779
Yong-Kui ZhangDepartment of Cardiothoracic Surgery, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang Province, China.ORCID 0000-0001-9339-6961
Han-Bo LeDepartment of Cardiothoracic Surgery, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang Province, China.ORCID 0000-0001-7738-5277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to develop and validate a clinical nomogram model for predicting overall survival (OS) in non-small-cell lung cancer (NSCLC) patients with resected tumors that were 30 mm or smaller, using clinical data and molecular marker findings. We retrospectively analyzed 786 NSCLC patients with a pathological tumor size less than 30 mm who underwent surgery between 2007 and 2017 at our institution. We identified and integrated significant prognostic factors to build the nomogram model using the training set, which was subjected to the internal data validation. The prognostic performance was calibrated and evaluated by the concordance index (C-index) and risk group stratification. Multivariable analysis identified the pathological tumor size, lymph node metastasis, and Ki-67 expression as independent prognostic factors, which were entered into the nomogram model. The nomogram-predicted probabilities of OS at 1 year, 3 years, and 5 years posttreatment represented optimal concordance with the actual observations. Harrell's C-index of the constructed nomogram with the training set was 0.856 (95% CI: 0.804-0.908), whereas TNM staging was 0.814 (95% CI: 0.742-0.886,

Indexed as

AgedCarcinoma, Non-Small-Cell LungFemaleHumansLung NeoplasmsLymphatic MetastasisMaleMiddle AgedPrognosisSurvival AnalysisTumor Burden

Identifiers

PMID31191756
PMCPMC6525952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.