Evidence map›Paper›PMID 31191752›Full record

ArticleDisease markers2019

Alvita Vilkeviciute, Loresa Kriauciuniene, Romanas Chaleckis, Vytenis Pranas Deltuva, Rasa Liutkeviciene

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Modeling complex age-related eye disease.Progress in retinal and eye research · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Haplotypes ofDisease markers · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alvita VilkeviciuteNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, LT-50161 Kaunas, Lithuania.ORCID 0000-0002-0427-5568
Loresa KriauciunieneNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, LT-50161 Kaunas, Lithuania.
Romanas ChaleckisGunma University Initiative for Advanced Research, Maebashi, Gunma 371-8512, Japan.
Vytenis Pranas DeltuvaNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, LT-50161 Kaunas, Lithuania.
Rasa LiutkevicieneNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, LT-50161 Kaunas, Lithuania.
Lithuanian University of Health Sciences · LTGunma University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAge-related macular degeneration (AMD) is a progressive neurodegenerative disease of a central part of the neural retina (macula) and a leading cause of blindness in elderly people. While it is known that the AMD is a multifactorial disease, genetic factors involved in lipid metabolism, inflammation, and neovascularization are currently being widely studied in genome-wide association studies (GWAS). The aim of our study was to evaluate the impact of new single nucleotide polymorphisms (SNPs) in

methodsCase-control study involved 254 patients diagnosed with early AMD, 244 patients with exudative AMD, and 942 control subjects. The genotyping of

resultsStatistically significant difference was found in genotype (TT, TC, and CC) distribution of

conclusionOur study revealed a strong association between a variant in

Indexed as

Polymorphism, Single NucleotideAgedCollagen Type VIIICollagen Type XDNA-Binding ProteinsFemaleHumansIntracellular Signaling Peptides and ProteinsMacular DegenerationMaleMiddle AgedProtein Serine-Threonine KinasesCOL10A1 protein, humanCol8A1 protein, humanCollagen Type VIIICollagen Type XDNA-Binding ProteinsIntracellular Signaling Peptides and ProteinsProtein Serine-Threonine KinasesRAD51B protein, humanTRIB1 protein, human

Identifiers

PMID31191752
PMCPMC6525907
OpenAlexW2943726992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.