Evidence map›Paper›PMID 31191680›Full record

ArticleStem cells international2019

Mesenchymal Stem Cells Derived and Cultured from Glioblastoma Multiforme Increase Tregs, Downregulate Th17, and Induce the Tolerogenic Phenotype of Monocyte-Derived Cells.

Kalina Tumangelova-Yuzeir, Emanuil Naydenov, Ekaterina Ivanova-Todorova, Ekaterina Krasimirova, Georgi Vasilev, Sevdalin Nachev, Dobroslav Kyurkchiev

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. The role and mechanism of IL‑35 in myasthenia gravis (Review).International journal of molecular medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kalina Tumangelova-YuzeirLaboratory of Clinical Immunology, University Hospital "St. Ivan Rilski," Department of Clinical Laboratory and Clinical Immunology, Medical University of Sofia, Sofia 1431, Bulgaria.
Emanuil NaydenovClinic of Neurosurgery, University Hospital "St. Ivan Rilski," Medical University Sofia, 15 "Acad. Ivan Geshov" Str., 1431 Sofia, Bulgaria.
Ekaterina Ivanova-TodorovaLaboratory of Clinical Immunology, University Hospital "St. Ivan Rilski," Department of Clinical Laboratory and Clinical Immunology, Medical University of Sofia, Sofia 1431, Bulgaria.
Ekaterina KrasimirovaLaboratory of Clinical Immunology, University Hospital "St. Ivan Rilski," Department of Clinical Laboratory and Clinical Immunology, Medical University of Sofia, Sofia 1431, Bulgaria.
Georgi VasilevLaboratory of Clinical Immunology, University Hospital "St. Ivan Rilski," Department of Clinical Laboratory and Clinical Immunology, Medical University of Sofia, Sofia 1431, Bulgaria.
Sevdalin NachevLaboratory of Clinical Pathology, University Hospital "St. Ivan Rilski," Medical University Sofia, 15 "Acad. Ivan Geshov" Str., 1431 Sofia, Bulgaria.
Dobroslav KyurkchievLaboratory of Clinical Immunology, University Hospital "St. Ivan Rilski," Department of Clinical Laboratory and Clinical Immunology, Medical University of Sofia, Sofia 1431, Bulgaria.ORCID 0000-0002-8257-7764
Medical University of Sofia · BGUniversity Hospital St. Ivan Rilski · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) possess immunosuppressive properties and have been described in the tumor microenvironment of glioblastoma multiforme (GBM). This manuscript has two major topics-first, to describe isolated and cultured MSCs derived from GBM (GB-MSCs) and second, to examine their

Identifiers

PMID31191680
PMCPMC6525812
OpenAlexW2943058049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.