Evidence map›Paper›PMID 31191637›Full record

ReviewNeural plasticity2019

Finding the Intersection of Neuroplasticity, Stroke Recovery, and Learning: Scope and Contributions to Stroke Rehabilitation.

Leeanne Carey, Alistair Walsh, Achini Adikari, Peter Goodin, Damminda Alahakoon, Daswin De Silva, Kok-Leong Ong, Michael Nilsson, Lara Boyd

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05405140 (Multiphasic Neuroplasticity Based Training Protocol With Shock Wave Therapy For Post Stroke Spasticity), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05405140 nacompletednot on this mapstarted 2022, after this paper: background citation

Multiphasic Neuroplasticity Based Training Protocol With Shock Wave Therapy For Post Stroke Spasticity

TypeinterventionalSponsorRiphah International UniversityRan2022 to 2023Enrolled32ConditionsStroke, Spasticity, MuscleArmsShock wave therapy with multiphasic neuroplasticity based training protocol, Conventional physical therapy
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  10. Supporting Long-Term Meaningful Outcomes in Stroke Rehabilitation.Current neurology and neuroscience reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leeanne CareyOccupational Therapy, School of Allied Health, Human Sciences and Sport, College of Science, Health and Engineering, La Trobe University, Bundoora, VIC 3086, Australia.ORCID 0000-0001-6376-8613
Alistair WalshOccupational Therapy, School of Allied Health, Human Sciences and Sport, College of Science, Health and Engineering, La Trobe University, Bundoora, VIC 3086, Australia.ORCID 0000-0001-8869-3590
Achini AdikariResearch Centre for Data Analytics and Cognition, La Trobe University, Bundoora, VIC 3086, Australia.ORCID 0000-0001-5112-5063
Peter GoodinNeurorehabilitation and Recovery, Stroke Division, Florey Institute of Neuroscience and Mental Health, Heidelberg VIC 3084, Australia.
Damminda AlahakoonResearch Centre for Data Analytics and Cognition, La Trobe University, Bundoora, VIC 3086, Australia.
Daswin De SilvaResearch Centre for Data Analytics and Cognition, La Trobe University, Bundoora, VIC 3086, Australia.
Kok-Leong OngResearch Centre for Data Analytics and Cognition, La Trobe University, Bundoora, VIC 3086, Australia.
Michael NilssonOccupational Therapy, School of Allied Health, Human Sciences and Sport, College of Science, Health and Engineering, La Trobe University, Bundoora, VIC 3086, Australia.ORCID 0000-0002-8826-1621
Lara BoydDjavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.ORCID 0000-0002-2828-4549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Neural plastic changes are experience and learning dependent, yet exploiting this knowledge to enhance clinical outcomes after stroke is in its infancy. Our aim was to search the available evidence for the core concepts of neuroplasticity, stroke recovery, and learning; identify links between these concepts; and identify and review the themes that best characterise the intersection of these three concepts. Methods: We developed a novel approach to identify the common research topics among the three areas: neuroplasticity, stroke recovery, and learning. A concept map was created Results: The search of the three concepts separately yielded 405,636 publications. Publications were filtered to include only human studies, generating 263,751 publications related to the concepts of neuroplasticity ( Discussion and Conclusions: Our novel approach developed for this review allowed the identification of the common themes/topics that intersect the concepts of neuroplasticity, stroke recovery, and learning. These may be synthesised to advance a neuroscience-informed approach to stroke rehabilitation. We also identified gaps in available literature using this approach. These may help guide future targeted research.

Indexed as

Stroke RehabilitationBrainHumansLearningNeuronal PlasticityNeuronsRecovery of FunctionStroke

Identifiers

PMID31191637
PMCPMC6525913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.