ReviewFrontiers in plant science2019
1-Aminocyclopropane-1-Carboxylic Acid Oxidase (ACO): The Enzyme That Makes the Plant Hormone Ethylene.
Review in Frontiers in plant science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 1 of them a synthesis that pooled it.
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Who cites it
178 citing papers in PubMed, 1 synthesis or guideline pooled it, 398 citations in OpenAlex.
- Integrated Meta-QTL analysis and transcriptomic profiling reveal genomic regions for fruit quality, abiotic and biotic stress resilience in cucumber (Cucumis sativus L.).BMC plant biology · 2026Pooled it
- Rhizobacterial biocontrol of potato late blight and genomic insights into disease suppression and growth promotion.iScience · 2026Article
- Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026Review
- Influence of Primary Coordination Sphere on Anion Rebound Selectivity in Nonheme Fe Enzyme-Catalyzed C(sp3)-H Functionalization: A Comparative Experimental and Computational Study of EgtB and ACCO.Journal of the American Chemical Society · 2026Article
- Influence of Primary Coordination Sphere on Anion Rebound Selectivity in Nonheme Fe Enzyme-Catalyzed C(spbioRxiv : the preprint server for biology · 2026Article
- Structural Characterization and Expression Profiling of Ethylene Biosynthetic Genes During AgNOInternational journal of molecular sciences · 2026Article
- Genome-wide identification and characterization of 1-amino-cyclopropane-1- carboxylate synthase (ACS) gene family in Carica papaya and expression insights in response to hormone stress.BMC plant biology · 2026Article
- Alternative oxidase and ethylene form a positive feed-forward loop in mitochondrial retrograde signaling.Plant communications · 2026Article
- Metabolic Enzyme MeHNL11 Regulates MeCAS1b Transcription for Cyanide Reutilization in Response to Nitrate Deficiency in Cassava.Plant biotechnology journal · 2026Article
- Transcriptomic analyses of piperitone inhibited sprouting of 'Yan 25' sweet potato storage roots.Food chemistry. Molecular sciences · 2026Article
- Cloning and functional determination of PpyASR1 during fruit development in Pyrus pyrifolia.BMC plant biology · 2026Article
- Hermaphroditism inPlants (Basel, Switzerland) · 2026Review
- Ethylene signaling and metabolite reprogramming in salt tolerance of Triticum aestivum.Scientific reports · 2026Article
- Structural and Functional Validation of Pseudomonas Savastanoi Ethylene Forming Enzymes Reveals Flexibility in 2-Oxoglutarate Binding Mode and Conformation.Chembiochem : a European journal of chemical biology · 2026Article
- Ethylene receptor gain- and loss-of-function mutants reveal an ETR1-dependent transcriptional network in Arabidopsis roots.Plant physiology · 2026Article
- Plant Growth-Promoting Yeasts fromJournal of agricultural and food chemistry · 2026Article
- Article
- Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening.Angewandte Chemie (International ed. in English) · 2026Article
- A century ofPlant signaling & behavior · 2025Review
- Bacillus velezensis Bac-9, isolated from kefir, possesses antifungal activity and improves resistance of tomato plant against whitefly Bemisia tabaci.BMC microbiology · 2025Article
118 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The volatile plant hormone ethylene regulates many plant developmental processes and stress responses. It is therefore crucial that plants can precisely control their ethylene production levels in space and time. The ethylene biosynthesis pathway consists of two dedicated steps. In a first reaction, S-adenosyl-L-methionine (SAM) is converted into 1-aminocyclopropane-1-carboxylic acid (ACC) by ACC-synthase (ACS). In a second reaction, ACC is converted into ethylene by ACC-oxidase (ACO). Initially, it was postulated that ACS is the rate-limiting enzyme of this pathway, directing many studies to unravel the regulation of ACS protein activity, and stability. However, an increasing amount of evidence has been gathered over the years, which shows that ACO is the rate-limiting step in ethylene production during certain dedicated processes. This implies that also the ACO protein family is subjected to a stringent regulation. In this review, we give an overview about the state-of-the-art regarding ACO evolution, functionality and regulation, with an emphasis on the transcriptional, post-transcriptional, and post-translational control. We also highlight the importance of ACO being a prime target for genetic engineering and precision breeding, in order to control plant ethylene production levels.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.