Evidence map›Paper›PMID 31191543›Full record

ArticleFrontiers in immunology2019

Differential Pathogenic Th17 Profile in Mesenteric Lymph Nodes of Crohn's Disease and Ulcerative Colitis Patients.

Marwa Bsat, Laurence Chapuy, Manuel Rubio, Ramses Wassef, Carole Richard, Frank Schwenter, Rasmy Loungnarath, Geneviève Soucy, Heena Mehta, Marika Sarfati

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 53 citations in OpenAlex.

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  9. Shared genetic association between inflammatory bowel disease and acute myeloid leukemia: insights from mendelian randomization and transcriptomic analyses.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Marwa BsatImmunoregulation Laboratory, Centre de Recherche du CHUM (CRCHUM), Montreal, QC, Canada.
Laurence ChapuyImmunoregulation Laboratory, Centre de Recherche du CHUM (CRCHUM), Montreal, QC, Canada.
Manuel RubioImmunoregulation Laboratory, Centre de Recherche du CHUM (CRCHUM), Montreal, QC, Canada.
Ramses WassefDepartment of Gastrointestinal Surgery, CHUM, Montreal, QC, Canada.
Carole RichardDepartment of Gastrointestinal Surgery, CHUM, Montreal, QC, Canada.
Frank SchwenterDepartment of Gastrointestinal Surgery, CHUM, Montreal, QC, Canada.
Rasmy LoungnarathDepartment of Gastrointestinal Surgery, CHUM, Montreal, QC, Canada.
Geneviève SoucyDepartment of Pathology, CHUM, Montreal, QC, Canada.
Heena MehtaImmunoregulation Laboratory, Centre de Recherche du CHUM (CRCHUM), Montreal, QC, Canada.
Marika SarfatiImmunoregulation Laboratory, Centre de Recherche du CHUM (CRCHUM), Montreal, QC, Canada.
Centre Hospitalier de l’Université de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The drug targets IL23 and IL12 regulate pathogenicity and plasticity of intestinal Th17 cells in Crohn's disease (CD) and ulcerative colitis (UC), the two most common inflammatory bowel diseases (IBD). However, studies examining Th17 dysregulation in mesenteric lymph nodes (mLNs) of these patients are rare. We showed that in mLNs, CD could be distinguished from UC by increased frequencies of CCR6

Indexed as

AdolescentAdultAgedAged, 80 and overColitis, UlcerativeCrohn DiseaseCytokinesFemaleGene Expression ProfilingHumansImmunologic MemoryInterleukin-17Lymph NodesMaleMesenteryMiddle AgedCytokinesInterleukin-17humaninflammatory bowel diseasemesenteric lymph nodesplasticityTh17 cells

Identifiers

PMID31191543
PMCPMC6547831
OpenAlexW2947844770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.