Evidence map›Paper›PMID 31191321›Full record

ArticleFrontiers in pharmacology2019

The Selective Rat Toxicant Norbormide Blocks K

Simona Saponara, Fabio Fusi, Ottavia Spiga, Alfonso Trezza, Brian Hopkins, Margaret A Brimble, David Rennison, Sergio Bova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Prokinetic effects ofPharmaceutical biology · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Simona SaponaraDepartment of Life Sciences, University of Siena, Siena, Italy.
Fabio FusiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Ottavia SpigaDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Alfonso TrezzaDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Brian HopkinsLandcare Research, Lincoln, New Zealand.
Margaret A BrimbleSchool of Chemical Sciences, University of Auckland, Auckland, New Zealand.
David RennisonSchool of Chemical Sciences, University of Auckland, Auckland, New Zealand.
Sergio BovaDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy.
University of Siena · ITUniversity of Auckland · NZUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Norbormide is a toxicant selective for rats to which it induces a widespread vasoconstriction. In a recent paper, we hypothesized a role of ATP-sensitive potassium (K

Indexed as

dockingglibenclamideKATP channelmolecular modelingnorbormidepatch-clamp

Identifiers

PMID31191321
PMCPMC6540933
OpenAlexW2946486622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.