ArticleFrontiers in computational neuroscience2019
A Role for Electrotonic Coupling Between Cortical Pyramidal Cells.
Article in Frontiers in computational neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Morphological details contribute to neuronal response variability within the same cell type.Frontiers in cellular neuroscience · 2026Article
- Modeling the role of gap junctions between excitatory neurons in the developing visual cortex.PLoS computational biology · 2021Article
- A computational investigation of electrotonic coupling between pyramidal cells in the cortex.Journal of computational neuroscience · 2020Article
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4 authors.
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Abstract
Many brain regions communicate information through synchronized network activity. Electrical coupling among the dendrites of interneurons in the cortex has been implicated in forming and sustaining such activity in the cortex. Evidence for the existence of electrical coupling among cortical pyramidal cells, however, has been largely absent. A recent experimental study measured properties of electrical connections between pyramidal cells in the cortex deemed "electrotonic couplings." These junctions were seen to occur pair-wise, sparsely, and often coexist with electrically-coupled interneurons. Here, we construct a network model to investigate possible roles for these rare, electrotonically-coupled pyramidal-cell pairs. Through simulations, we show that electrical coupling among pyramidal-cell pairs significantly enhances coincidence-detection capabilities and increases network spike-timing precision. Further, a network containing multiple pairs exhibits large variability in its firing pattern, possessing a rich coding structure.
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