Evidence map›Paper›PMID 31191233›Full record

ArticleFrontiers in neuroscience2019

Fibrinogen Chains Intrinsic to the Brain.

Eugene V Golanov, Martyn A Sharpe, Angelique S Regnier-Golanov, Gregory J Del Zoppo, David S Baskin, Gavin W Britz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

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  7. Re-framing the importance of Group BInfection and immunity · 2024
    Review
  8. Article
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  11. The role of fibrinogen in traumatic brain injury: from molecular pathological mechanisms to clinical management.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Review
  12. Article
  13. Commonly Overlooked Factors in Biocompatibility Studies of Neural Implants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  14. Article
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  19. A new perspective on cerebrospinal fluid dynamics after subarachnoid hemorrhage: From normal physiology to pathophysiological changes.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eugene V GolanovDepartment of Neurosurgery, Houston Methodist Hospital, Houston, TX, United States.
Martyn A SharpeDepartment of Neurosurgery, Houston Methodist Hospital, Houston, TX, United States.
Angelique S Regnier-GolanovDepartment of Neurosurgery, Houston Methodist Hospital, Houston, TX, United States.
Gregory J Del ZoppoDivision of Hematology, University of Washington School of Medicine, Seattle, WA, United States.
David S BaskinDepartment of Neurosurgery, Houston Methodist Hospital, Houston, TX, United States.
Gavin W BritzDepartment of Neurosurgery, Houston Methodist Hospital, Houston, TX, United States.
Methodist Hospital · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We observed fine fibrin deposition along the paravascular spaces in naive animals, which increased dramatically following subarachnoid hemorrhage (SAH). Following SAH, fibrin deposits in the areas remote from the hemorrhage. Traditionally it is thought that fibrinogen enters subarachnoid space through damaged blood brain barrier. However, deposition of fibrin remotely from hemorrhage suggests that fibrinogen chains Aα, Bβ, and γ can originate in the brain. Here we demonstrate

Indexed as

astrocytesbrainfibrinfibrinogenfibrinogen chainintrinsicneuronssubarachnoid hemorrhage

Identifiers

PMID31191233
PMCPMC6549596
OpenAlexW2947947752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.