Evidence map›Paper›PMID 31191193›Full record

ReviewTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie2019

Microbiological Screening of Platelet Concentrates in Europe.

Marcel Prax, Isabelle Bekeredjian-Ding, Oleg Krut

Abstract readReview
In one paragraph

Review in Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Alterations in RNA Expression Profile FollowingInternational journal of molecular sciences · 2025
    Article
  5. How do we transfuse children in Italy? Results of a national survey.Blood transfusion = Trasfusione del sangue · 2025
    Article
  6. Enhanced invasion and survival of antibiotic- resistantFrontiers in cellular and infection microbiology · 2025
    Article
  7. Impact of Shelf-Life Extension on Platelet Availability: Results from an Inventory Management Modeling Study.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2024
    Article
  8. Growth and Distribution of Bacteria in Contaminated Whole Blood and Derived Blood Components.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2024
    Article
  9. Review
  10. Chemical and Microbiological Changes of Expired Platelet Concentrate.International journal of general medicine · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. PRP and PRF-Subgroups and Divisions When Used in Dentistry.Journal of personalized medicine · 2021
    Review
  18. Article
  19. Article
  20. Infectious Screening of Blood Components: Is There Still a Need for Further Inventions?Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marcel PraxDivision of Microbiology, Paul Ehrlich Institute, Langen, Germany.
Isabelle Bekeredjian-DingDivision of Microbiology, Paul Ehrlich Institute, Langen, Germany.
Oleg KrutDivision of Microbiology, Paul Ehrlich Institute, Langen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The risk of transfusion-associated sepsis due to transmission of bacteria is a persistent problem in the transfusion field. Despite numerous interventions to reduce the risk, cases of bacterial sepsis following transfusion are repeatedly being reported. Especially platelet concentrates are highly susceptible to bacterial contaminations due to the growth-promoting storage conditions. In Europe, blood establishments and national authorities have implemented individual precaution measures to mitigate the risk of bacterial transmission. To obtain an overview of the different approaches, we compiled information from national authorities, blood establishments, and the current literature. Several aspects such as the shelf life of platelets, time of sampling and the applied control measures are compared between the member states. The analysis of the data revealed a broad heterogeneity of procedures on a national level ranging from platelet release without any safety testing up to mandatory screening of all platelet concentrates prior to transfusion. Despite the substantial progress made in recent years, several bacterial reports on transfusion-associated sepsis indicate that further efforts are needed to increase the safety of blood transfusions in the long term.

Indexed as

Bacterial contaminationBlood safetyInfectionPathogen inactivationPlatelet concentratesSepsisTransfusion-associated infections

Identifiers

PMID31191193
PMCPMC6514488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.