ArticleLighting research & technology (London, England : 2001)2019
Effect of exposure duration and light spectra on nighttime melatonin suppression in adolescents and adults.
Article in Lighting research & technology (London, England : 2001), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Effects of bright light therapy for depression during pregnancy: a randomised, double-blind controlled trial.BMJ open · 2020Trial
- Screen exposure and mediators of executive function in children with ADHD.Pediatric research · 2026Article
- Comparative Effects of Red and Blue LED Light on Melatonin Levels During Three-Hour Exposure in Healthy Adults.Life (Basel, Switzerland) · 2025Article
- The Circadian Response to Evening Light Spectra in Early Childhood: Preliminary Insights.Journal of biological rhythms · 2025Article
- Serum 25-hydroxyvitamin D concentration is associated with device-estimated sleep metrics in healthy young and early middle-aged adults.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Regulating addictive algorithms and designs: protecting older adults from digital exploitation beyond a youth-centric approach.Frontiers in psychology · 2025Article
- Relative importance of intensity and spectrum of artificial light at night in disrupting behavior of a nocturnal rodent.The Journal of experimental biology · 2024Article
- Days to re-entrainment following the spring and autumn changes in local clock time: Beyond simple heuristics.Frontiers in photonics · 2024Article
- Effects of evening smartphone use on sleep and declarative memory consolidation in male adolescents and young adults.Brain communications · 2024Article
- Review on age-related differences in non-visual effects of light: melatonin suppression, circadian phase shift and pupillary light reflex in children to older adults.Journal of physiological anthropology · 2023Review
- Seasonality of brain function: role in psychiatric disorders.Translational psychiatry · 2023Review
- Electric lighting, adolescent sleep and circadian outcomes, and recommendations for improving light health.Sleep medicine reviews · 2022Review
- Predicting melatonin suppression by light in humans: Unifying photoreceptor-based equivalent daylight illuminances, spectral composition, timing and duration of light exposure.Journal of pineal research · 2022Article
- Current Insights into Optimal Lighting for Promoting Sleep and Circadian Health: Brighter Days and the Importance of Sunlight in the Built Environment.Nature and science of sleep · 2022Review
- Spatial sensitivity of human circadian response: Melatonin suppression from on-axis and off-axis light exposures.Neurobiology of sleep and circadian rhythms · 2021Article
- Review
- Modeling Circadian Phototransduction: Quantitative Predictions of Psychophysical Data.Frontiers in neuroscience · 2021Article
- Efficacy and safety of supplemental melatonin for delayed sleep-wake phase disorder in children: an overview.Sleep medicine: X · 2020Review
- Predictions of melatonin suppression during the early biological night and their implications for residential light exposures prior to sleeping.Scientific reports · 2020Article
- Melatonin inhibits Warburg-dependent cancer by redirecting glucose oxidation to the mitochondria: a mechanistic hypothesis.Cellular and molecular life sciences : CMLS · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
This study investigated how light exposure duration affects melatonin suppression, a well-established marker of circadian phase, and whether adolescents (13-18 years) are more sensitive to short-wavelength (blue) light than adults (32-51 years). Twenty-four participants (12 adolescents, 12 adults) were exposed to three lighting conditions during successive 4-h study nights that were separated by at least one week. In addition to a dim light (<5 lux) control, participants were exposed to two light spectra (warm (2700 K) and cool (5600 K)) delivering a circadian stimulus of 0.25 at eye level. Repeated measures analysis of variance revealed a significant main effect of exposure duration, indicating that a longer duration exposure suppressed melatonin to a greater degree. The analysis further revealed a significant main effect of spectrum and a significant interaction between spectrum and participant age. For the adolescents, but not the adults, melatonin suppression was significantly greater after exposure to the 5600 K intervention (43%) compared to the 2700 K intervention (29%), suggesting an increased sensitivity to short-wavelength radiation. These results will be used to extend the model of human circadian phototransduction to incorporate factors such as exposure duration and participant age to better predict effective circadian stimulus.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.