ReviewPsychology research and behavior management2019
Sexual dimorphism of oxytocin and vasopressin in social cognition and behavior.
Review in Psychology research and behavior management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- The novel vasopressin receptor (V1aR) antagonist SRX246 reduces anxiety in an experimental model in humans: a randomized proof-of-concept study.Psychopharmacology · 2021Trial
- Early life stress modulates social behavior via oxytocin and arginine vasopressin in males.European archives of psychiatry and clinical neuroscience · 2026Article
- The aporetic dialogues of Modena on gender differences: Is it all about testosterone? Episode II: Empathy.Andrology · 2026Review
- Interplay of plasma Oxytocin and oxytocin receptor gene methylation levels on empathy in older adults.Scientific reports · 2025Article
- The Role of Oxytocin and Oxytocin Gene Receptor Methylation During Withdrawal Therapy in Males With Alcohol Use Disorder.Addiction biology · 2025Article
- Effects of systemic oxytocin receptor activation and blockade on risky decision making in female and male rats.Behavioral neuroscience · 2025Article
- Article
- Evolutionary conserved peptide and glycoprotein hormone-like neuroendocrine systems in C. elegans.Molecular and cellular endocrinology · 2024Article
- Supraphysiological testosterone levels from anabolic steroid use and reduced sensitivity to negative facial expressions in men.Psychopharmacology · 2024Article
- Methylation of the Oxytocin, Oxytocin Receptor, and Vasopressin Gene Promoters in Tobacco Use Disorder during Cessation.Neuropsychobiology · 2024Article
- Water intake, hydration status and 2-year changes in cognitive performance: a prospective cohort study.BMC medicine · 2023Article
- Evaluating the neuropeptide-social cognition link in ageing: the mediating role of basic cognitive skills.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Oxytocin in Women's Health and Disease.Frontiers in endocrinology · 2022Review
- The Interplay of Sex Steroids, the Immune Response, and the Intestinal Microbiota.Trends in microbiology · 2021Review
- Genetic and morphological estimates of androgen exposure predict social deficits in multiple neurodevelopmental disorder cohorts.Molecular autism · 2021Article
- The social network: Neural control of sex differences in reproductive behaviors, motivation, and response to social isolation.Current opinion in neurobiology · 2021Review
- Limbic Neuropeptidergic Modulators of Emotion and Their Therapeutic Potential for Anxiety and Post-Traumatic Stress Disorder.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Review
- Cell-type specific knockout of peptidylglycine α-amidating monooxygenase reveals specific behavioral roles in excitatory forebrain neurons and cardiomyocytes.Genes, brain, and behavior · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neuropeptides oxytocin (OT) and vasopressin (VP) are hormones that are known to mediate social behavior and cognition, but their influence may be sex-dependent. This paper aims to provide a comprehensive review of the sex-related influence of OT and VP on social cognition, focusing on partner preference and sexual orientation, trust and relevant behaviors, memory modulation, and emotion regulation. Most studies have suggested that OT facilitates familiar-partner preference in both sexes, with females being more significant, increased trust in others, especially for male, enhanced memory in either sex, and reduced anxious emotion in males. However, VP-regulated social cognition has been less studied. Other relevant studies have indicated that VP facilitated familiar-partner preference, improved memory, induced empathy formation, increased positive-emotion recognition, and induced anxiety without any sex difference. However, there was a male preponderance among studies, and results were often too complex to draw firm conclusions. Clarifying the interplay between OT/VP and sex hormones in the regulation of social cognition is necessary for further applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.