Evidence map›Paper›PMID 31190814›Full record

ArticleInternational journal of nanomedicine2019

Integration of PEG 400 into a self-nanoemulsifying drug delivery system improves drug loading capacity and nasal mucosa permeability and prolongs the survival of rats with malignant brain tumors.

Yu-Shuan Chen, Yu-Han Chiu, Yuan-Sheng Li, En-Yi Lin, Dean-Kuo Hsieh, Chia-Hung Lee, Mao-Hsuan Huang, Hong-Meng Chuang, Shinn-Zong Lin, Horng-Jyh Harn and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yu-Shuan ChenBioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, Republic of China.
Yu-Han ChiuDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan, Republic of China.
Yuan-Sheng LiDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan, Republic of China.
En-Yi LinDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan, Republic of China.
Dean-Kuo HsiehDepartment and Graduate Institute of Applied Chemistry, Chaoyang University of Technology, Taichung, Taiwan, Republic of China.
Chia-Hung LeeDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan, Republic of China.
Mao-Hsuan HuangBioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, Republic of China.
Hong-Meng ChuangBioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, Republic of China.
Shinn-Zong LinBioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, Republic of China.
Horng-Jyh HarnBioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, Republic of China.
Tzyy-Wen ChiouDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan, Republic of China.
National Dong Hwa University · TWTzu Chi Foundation · TWChaoyang University of Technology · TWTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Delivery SystemsAnimalsBrain NeoplasmsCell DeathCell Line, TumorEmulsionsGliomaHumansInhibitory Concentration 50MaleNanoparticlesNasal MucosaParticle SizePermeabilityPhthalic AnhydridesPolyethylene GlycolsbutylidenephthalideEmulsionsPhthalic Anhydridespolyethylene glycol 400Polyethylene GlycolsSurface-Active Agentsbutylidenephthalideglioblastomaintranasal administrationloading capacitypermeabilitypolyethylene glycol 400

Identifiers

PMID31190814
PMCPMC6530554
OpenAlexW2946461346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.