Evidence map›Paper›PMID 31190773›Full record

ArticleClinical interventions in aging2019

The relationship between blood-brain barrier permeability and enlarged perivascular spaces: a cross-sectional study.

Yue Li, Man Li, Lei Yang, Wei Qin, Shuna Yang, Junliang Yuan, Tao Jiang, Wenli Hu

Open access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. The role of glymphatic dysfunction in cerebral small vessel disease and vascular cognitive impairment, and therapeutic implications.International journal of stroke : official journal of the International Stroke Society · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Enlarging and shrinking focal perivascular spaces.The neuroradiology journal · 2025
    Review
  16. Observational
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yue LiDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Man LiDepartment of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Lei YangDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Wei QinDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Shuna YangDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Junliang YuanDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Tao JiangDepartment of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Wenli HuDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAged, 80 and overBasal GangliaBiomarkersBlood-Brain BarrierCerebral Small Vessel DiseasesCross-Sectional StudiesFemaleGlymphatic SystemHumansLogistic ModelsMagnetic Resonance ImagingMaleMiddle AgedBiomarkersblood–brain barriercerebral small vessel diseaseDCEdynamic contrast-enhancedenlarged perivascular spacesmagnetic resonance imagingMRI

Identifiers

PMID31190773
PMCPMC6519012
OpenAlexW2944504351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.