Evidence map›Paper›PMID 31190621›Full record

Trial reportPharmacogenomics2019

Effects of

Jacqueline M Dempsey, Kelley M Kidwell, Christina L Gersch, Andrea M Pesch, Zeruesenay Desta, Anna Maria Storniolo, Vered Stearns, Todd C Skaar, Daniel F Hayes, N Lynn Henry and 2 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pharmacogenomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Genetic Influences in Breast Cancer Drug Resistance.Breast cancer (Dove Medical Press) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jacqueline M DempseyDepartment of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI 48109-1065, USA.
Kelley M KidwellDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.
Christina L GerschDepartment of Internal Medicine, Division of Hematology/Oncology, Medical School, University of Michigan, Ann Arbor, MI 48109, USA.
Andrea M PeschDepartment of Internal Medicine, Division of Hematology/Oncology, Medical School, University of Michigan, Ann Arbor, MI 48109, USA.
Zeruesenay DestaDepartment of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Anna Maria StornioloDepartment of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Vered StearnsDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21231, USA.
Todd C SkaarDepartment of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Daniel F HayesDepartment of Internal Medicine, Division of Hematology/Oncology, Medical School, University of Michigan, Ann Arbor, MI 48109, USA.
N Lynn HenryDepartment of Internal Medicine, Division of Hematology/Oncology, Medical School, University of Michigan, Ann Arbor, MI 48109, USA.
James M RaeDepartment of Internal Medicine, Division of Hematology/Oncology, Medical School, University of Michigan, Ann Arbor, MI 48109, USA.
Daniel L HertzDepartment of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI 48109-1065, USA.ORCID 0000-0003-0501-1035
University of Michigan · USIndiana University – Purdue University Indianapolis · USGTx (United States) · USJohns Hopkins University · US

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alexey I Nesvizhskii · 1988 to 2026
$178.2M
ZINC GLUCONATE GLYCINE LOZENGES &VITAMIN C EFFECTS ON COMMON COLDM01RR000042 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELSTROM, REBECCA L · 1985 to 2007
$40.8M
ZINC AND CA EDTA THERAPY OF PLUMBISMM01RR000052 · NCRR · JOHNS HOPKINS UNIVERSITY · PI MARSH, LAURA · 1985 to 2007
$37.3M
ZOSUQUIDAR TRIHYDROCHLORIDE DURING CONVENTIONAL INDUCTION AND POST-REMISSIONM01RR000750 · NCRR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI STORNIOLO, ANNA · 1985 to 2008
$25.5M
TAMAXIFEN PHARMACOGENETICSU01GM061373 · NIGMS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FLOCKHART, DAVID ALASTAIR · 2000 to 2009
$17.0M
Indiana University Comprehensive Training in Clinical PharmacologyT32GM008425 · NIGMS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Zeruesenay Desta, Michael Thomas Eadon · 1992 to 2026
$7.7M
Biostatistics Training Program in Cancer ResearchT32CA083654 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Veerabhadran Baladandayuthapani, Kelley McLain Kidwell · 2002 to 2026
$4.3M
Genetic Predictors of Anti-Estrogen Clinical Activity in Breast Cancer PatientsR01GM099143 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAE, JAMES MICHAEL · 2011 to 2015
$1.6M
NCI NIH HHS P30 CA046592NCI NIH HHS T32 CA083654NCRR NIH HHS M01 RR000042NCRR NIH HHS M01 RR000052NCRR NIH HHS M01 RR000750NIGMS NIH HHS R01 GM099143NIGMS NIH HHS T32 GM008425NIGMS NIH HHS U01 GM061373
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AndrostadienesAromatase InhibitorsBreast NeoplasmsEstrogen Receptor alphaEstrogensFemaleGenotypeHumansLetrozoleLiver-Specific Organic Anion Transporter 1Middle AgedPharmacogeneticsPolymorphism, GeneticTamoxifenAndrostadienesAromatase InhibitorsESR1 protein, humanEstrogen Receptor alphaEstrogensexemestaneLetrozoleLiver-Specific Organic Anion Transporter 1SLCO1B1 protein, humanTamoxifenbreast cancerexemestaneletrozolepharmacogenomics

Identifiers

PMID31190621
PMCPMC6891932
OpenAlexW2950547942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.