SynthesisDigestive diseases and sciences2019
A Risk Assessment of Factors for the Presence of Angiodysplasias During Endoscopy and Factors Contributing to Symptomatic Bleeding and Rebleeds.
Synthesis in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Characteristics and outcomes of small-bowel vascular lesions and nonvascular lesions in patients with suspected small-bowel bleeding detected by deep enteroscopy: a single-center experience in Taiwan.BMC gastroenterology · 2026Article
- Right Hemicolectomy for Refractory Hematochezia in Cecal Angiodysplasia After Failed Embolization: A Case Report.Cureus · 2026Article
- Comorbidity burden and outcomes of endoscopic ultrasound-guided treatment of pancreatic fluid collections: Multicenter study with nationwide data-based validation.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025Article
- Higher waist circumference as a risk factor for rebleeding of small bowel angiodysplasia.Translational gastroenterology and hepatology · 2025Article
- Gastrointestinal Angiodysplasia Resolution After Transcatheter Aortic Valve Implantation.JAMA network open · 2024Article
- Small-Bowel Angioectasias: Are They Responsible for a Real Impact on Survival?GE Portuguese journal of gastroenterology · 2023Article
- Nationwide cohort study identifies clinical outcomes of angioectasia in patients with acute hematochezia.Journal of gastroenterology · 2023Article
- Reduction of Gastrointestinal Bleeding in Patients With Heyde Syndrome Undergoing Transcatheter Aortic Valve Implantation.Circulation. Cardiovascular interventions · 2022Article
- Rebleeding Rate and Risk Factors for Rebleeding after Device-Assisted Enteroscopy in Patients with Obscure Gastrointestinal Bleeding: A KASID Multicenter Study.Diagnostics (Basel, Switzerland) · 2022Article
- Deep Learning and Device-Assisted Enteroscopy: Automatic Detection of Gastrointestinal Angioectasia.Medicina (Kaunas, Lithuania) · 2021Article
- Scoring systems in clinical small-bowel capsule endoscopy: all you need to know!Endoscopy international open · 2021Review
- Risk Stratification of Angioectasia as a Cause of Gastrointestinal Bleeding: Untangling the Spider's Web?Digestive diseases and sciences · 2019Article
- Artificial intelligence and capsule endoscopy: automatic detection of vascular lesions using a convolutional neural network.Annals of gastroenterologyArticle
Corrections and comments
- Commented on by
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have assessed factors associated with angiodysplasias during endoscopy or factors associated with symptomatic disease.
aimsTo evaluate risk factors for the presence of and contribution to symptomatic disease in patients with angiodysplasias.
methodsWe performed a systematic MEDLINE, EMBASE and Cochrane Library search according to the PRISMA guidelines for studies assessing risk factors involved in angiodysplasias detected during endoscopy and factors that lead to anemia or overt bleeding. Study quality was assessed with the Newcastle-Ottawa scale. A risk assessment was performed by selecting risk factors identified by two independent studies and/or by a large effect size.
resultsTwenty-three studies involving 92,634 participants were included. The overall quality of the evidence was moderate. Risk factors for the diagnosis of angiodysplasias during endoscopy confirmed by at least two studies were increasing age (OR 1.09 per year, 95% CI 1.04-1.1), chronic kidney disease (OR 4.5, 95% CI 1.9-10.5) and cardiovascular disease (2.9, 95% CI 1.4-6.2). The risk of rebleeds was higher in the presence of multiple lesions (OR 4.2, 95% CI 1.1-16.2 and 3.8, 95% CI 1.3-11.3 and 8.6, 95% CI 1.4-52.6), liver cirrhosis (OR 4.0, 95% 1.1-15.0) and prothrombin time < 30% (OR 4.2, 95% 1.1-15.4) with a moderate effect size. Multiple comorbidities were associated with an increased in-hospital mortality (OR 2.29, 95% CI 1.2-4.3).
conclusionsThis systematic review identified age, chronic kidney disease and cardiovascular disease as the most important risk factors for the diagnosis of angiodysplasias during endoscopy. Multiple lesions increase the risk of recurrent bleeding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.