ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2019
Appetite is correlated with octopamine and hemolymph sugar levels in forager honeybees.
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- Hungry for Knowledge: Octopamine Signaling Regulates Hunger-Enhanced Olfactory Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Honey bees are resilient to the long-term presence of alcohol in their diet.Ecotoxicology (London, England) · 2025Article
- Age dominates flight distance and duration, while body size shapes flight speed inProceedings. Biological sciences · 2024Article
- Regulation of forager honey bee appetite independent of the glucose-insulin signaling pathway.Frontiers in insect science · 2024Article
- Gustatory Responsiveness of Honey Bees Colonized with a Defined or Conventional Gut Microbiota.Microbes and environments · 2024Article
- Age-Dependent Honey Bee Appetite Regulation Is Mediated by Trehalose and Octopamine Baseline Levels.Insects · 2021Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 4 countries.
Funding
Abstract
Insects have rapidly changing energy demands, so they primarily rely on hemolymph and other carbohydrates to carry out life activities. However, how gustatory responsiveness and hemolymph sugar levels coordinate with one another to maintain energetic homeostasis in insects remains largely unknown for the highly social honeybee that goes through large physiological and behavioral changes. The potential role of biogenic amines and neuropeptides in the connection between the regulation of appetite and fluctuating sugar levels in the hemolymph, due to starvation, as the bee ages, was investigated. The largest appetite increase due to the starvation treatment was within the forager age class and this corresponded with an increase in octopamine levels in the brain along with a decline in hemolymph sugar levels. Adipokinetic hormone (AKH) was found in very small quantities in the brain and there were no significant changes in response to starvation treatment. Our findings suggest that the particularly dynamic levels of hemolymph sugar levels may serve as a monitor of the forager honeybee energetic state. Therefore, there may be a pathway in forager bees via octopamine responsible for their precise precipitous regulation of appetite, but to determine cause and effect relationships further investigation is needed.
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