ArticleScientific reports2019
Oxidative stress and mitochondrial responses to stress exposure suggest that king penguins are naturally equipped to resist stress.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 58 citations in OpenAlex.
- Evaluation of the stress state based on fecal corticosterone metabolite concentrations in captive penguins in Japan.The Journal of veterinary medical science · 2024Article
- Social, not genetic, programming of development and stress physiology of a colonial seabird.Proceedings. Biological sciences · 2024Article
- An evolving roadmap: using mitochondrial physiology to help guide conservation efforts.Conservation physiology · 2024Article
- Seasonal plasticity in immunocompetent cytokines (IL-2, IL-6, and TNF-α), myeloid progenitor cell (CFU-GM) proliferation, and LPS-induced oxido-inflammatory aberrations in a tropical rodent Funambulus pennanti: role of melatonin.Cell stress & chaperones · 2023Article
- Fitness correlates of blubber oxidative stress and cellular defences in grey seals (Halichoerus grypus): support for the life-history-oxidative stress theory from an animal model of simultaneous lactation and fasting.Cell stress & chaperones · 2023Article
- Short- and long-term consequences of heat exposure on mitochondrial metabolism in zebra finches (Taeniopygia castanotis).Oecologia · 2023Article
- Oxidative physiology of two small and highly migratory Arctic seabirds: Arctic terns (Conservation physiology · 2023Article
- Article
- Mitochondrial oxidative phosphorylation response overrides glucocorticoid-induced stress in a reptile.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022Article
- Positive selection over the mitochondrial genome and its role in the diversification of gentoo penguins in response to adaptation in isolation.Scientific reports · 2022Article
- Segmentation of Drug-Treated Cell Image and Mitochondrial-Oxidative Stress Using Deep Convolutional Neural Network.Oxidative medicine and cellular longevity · 2022Article
- Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model.Journal of cellular and molecular medicine · 2021Article
- Inferring Whole-Organism Metabolic Rate From Red Blood Cells in Birds.Frontiers in physiology · 2021Article
- Pace and stability of embryonic development affect telomere dynamics: an experimental study in a precocial bird model.Proceedings. Biological sciences · 2020Article
- Age-dependent impairment of adipose-derived stem cells isolated from horses.Stem cell research & therapy · 2020Article
- Assessment of fecal steroid and thyroid hormone metabolites in eastern North Pacific gray whales.Conservation physiology · 2020Article
- Is there an oxidative cost of acute stress? Characterization, implication of glucocorticoids and modulation by prior stress experience.Proceedings. Biological sciences · 2019Article
- The Relationship between Hormones, Glucose, and Oxidative Damage Is Condition and Stress Dependent in a Free-Living Passerine Bird.Physiological and biochemical zoology : PBZArticle
- Plan ahead, or wing it? How storm-petrel parents adjust food delivery to young chicks.Behavioral ecology : official journal of the International Society for Behavioral EcologyArticle
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 6 countries.
Funding
Abstract
Exposure to unpredictable environmental stressors could influence animal health and fitness by inducing oxidative stress, potentially through downstream effects of glucocorticoid stress hormones (e.g. corticosterone) on mitochondrial function. Yet, it remains unclear whether species that have evolved in stochastic and challenging environments may present adaptations to alleviate the effects of stress exposure on oxidative stress. We tested this hypothesis in wild king penguins by investigating mitochondrial and oxidative stress responses to acute restraint-stress, and their relationships with baseline (potentially mirroring exposure to chronic stress) and stress-induced increase in corticosterone levels. Acute restraint-stress did not significantly influence mitochondrial function. However, acute restraint-stress led to a significant increase in endogenous antioxidant defences, while oxidative damage levels were mostly not affected or even decreased. High baseline corticosterone levels were associated with an up-regulation of the glutathione antioxidant system and a decrease in mitochondrial efficiency. Both processes might contribute to prevent oxidative damage, potentially explaining the negative relationship observed between baseline corticosterone and plasma oxidative damage to proteins. While stress exposure can represent an oxidative challenge for animals, protective mechanisms like up-regulating antioxidant defences and decreasing mitochondrial efficiency seem to occur in king penguins, allowing them to cope with their stochastic and challenging environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.