ArticleScientific reports2019
The effects of comorbidity on colorectal cancer mortality in an Australian cancer population.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mortality rate and predictors of colorectal cancer patients in Ethiopia: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Return to work in elderly population with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Charleson and Elixhauser Comorbidity Indices in Predicting Mortality Among Young and Old Cervical Cancer Patients.Cancer medicine · 2026Article
- Multilevel insights into obesity, race/ethnicity, and survival in early-onset colorectal cancer in Georgia.Cancer causes & control : CCC · 2026Article
- National Trends in Rectal Cancer Among Younger Patients: A National Cancer Database Analysis.Cureus · 2026Article
- Sex differences in the impact of multimorbidity on long-term mortality for patients with colorectal cancer: a population registry-based cohort study.Journal of public health (Oxford, England) · 2025Article
- Follow-Up Adherence After Treatment With Curative Intent for Stage II and III Colorectal Cancer Patients.Cancer medicine · 2025Article
- The Impact of Radiation Proctopathy on Secondary-Primary Colorectal Cancer in Patients with Prostate Cancer.Journal of gastrointestinal cancer · 2025Article
- Comparison of Comorbidity Models Within a Population-Based Cohort of Older Adults With Non-Hodgkin Lymphoma.JCO clinical cancer informatics · 2024Article
- Real-World Experience of Immune-Checkpoint Inhibitors in Older Patients with Advanced Cutaneous Squamous Cell Carcinoma.Drugs & aging · 2024Article
- The intersection of heart failure and cancer in women: a review.Frontiers in cardiovascular medicine · 2024Review
- The Demographic Profile of Colorectal Cancer Patients in Indonesia: Insights from a Single Center Experience and Exploration of Immune Response and Survival Outcomes.F1000Research · 2024Article
- Variation in colorectal cancer treatment and outcomes in Scotland: real world evidence from national linked administrative health data.International journal of population data science · 2024Article
- Comorbidity Patterns in Patients Newly Diagnosed With Colorectal Cancer: Network-Based Study.JMIR public health and surveillance · 2023Observational
- Prevalence of comorbidities and their impact on survival among older adults with the five most common cancers in Taiwan: a population study.Scientific reports · 2023Article
- Associations of advanced age with comorbidity, stage and primary subsite as contributors to mortality from colorectal cancer.Frontiers in public health · 2023Article
- Feasibility of Support by Family Practitioners in Reducing Colorectal Cancer-Related Death among Outpatients Who Have Not Undergone Colorectal Cancer Screening.Diagnostics (Basel, Switzerland) · 2022Article
- Determining the Risk Factors Affecting on Death Due to Colorectal Cancer Progression: Survival Analysis in the Presence of Competing Risks.Journal of gastrointestinal cancer · 2022Article
- Impact of Socioeconomic Status on Cancer Incidence Risk, Cancer Staging, and Survival of Patients with Colorectal Cancer under Universal Health Insurance Coverage in Taiwan.International journal of environmental research and public health · 2021Article
- Head and neck melanoma: outcome and predictors in a population-based cohort study.Head & face medicine · 2021Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study estimated the absolute risk of colorectal cancer (CRC) specific and other-cause mortality using data from the population-based South Australian Cancer Registry. The impact of competing risks on the absolute and relative risks of mortality in cases with and without comorbidity was also investigated. The study included 7115 staged, primary CRC cases diagnosed between 2003 and 2012 with at least one year of follow-up. Comorbidities were classified according to Charlson, Elixhauser and C3 comorbidity indices, using hospital inpatient diagnoses occurring five years before CRC diagnosis. To estimate the differences in measures of association, the subdistribution hazard ratios (sHR) for the effect of comorbidity on mortality from the Fine and Gray model were compared to the cause-specific hazards (HR) from Cox regression model. CRC was most commonly diagnosed in people aged ≧ 70 years. In cases without comorbidity, the 10-year cumulative probability of CRC and other cause mortality were 37.1% and 17.2% respectively. In cases with Charlson comorbidity scores ≥2, the 10-year cumulative probability of CRC-specific and other cause mortality was 45.5% and 32.2%, respectively. Comorbidity was associated with increased CRC-specific and other cause mortality and the effect differed only marginally based on comorbidity index used.
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