Evidence map›Paper›PMID 31189923›Full record

ArticleNature communications2019

The transcription factor Slug represses p16

Pei Zhu, Chunping Zhang, Yongxing Gao, Furen Wu, Yalu Zhou, Wen-Shu Wu

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. The impact of cellular senescence on aging skeletal muscle.Frontiers in cell and developmental biology · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Epithelial-mesenchymal transition in tissue repair and degeneration.Nature reviews. Molecular cell biology · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pei ZhuDepartment of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Chunping ZhangDepartment of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Yongxing GaoDepartment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Furen WuDepartment of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Yalu ZhouDepartment of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Wen-Shu WuDepartment of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA. wuwenshu@uic.edu.
University of Illinois Chicago · USJohns Hopkins University · US

Funding

Regulatory Role of Transcription Factor Slug in AgingR01AG040182 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WU, WEN-SHU · 2011 to 2015
$1.6M
NIA NIH HHS R01 AG040182U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) 1R01AG040182
6 · The paper itself

Abstract

Activation of the p16

Indexed as

AgingAnimalsCell Self RenewalCellular SenescenceCyclin-Dependent Kinase Inhibitor p16FemaleGene Expression RegulationMaleMiceMice, Inbred C57BLMice, KnockoutModels, AnimalSatellite Cells, Skeletal MuscleSnail Family Transcription FactorsCdkn2a protein, mouseCyclin-Dependent Kinase Inhibitor p16Snai2 protein, mouseSnail Family Transcription Factors

Identifiers

PMID31189923
PMCPMC6561969
OpenAlexW2950729524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.