Evidence map›Paper›PMID 31189724›Full record

ArticleJournal of medical ethics2019

Ethical issues raised by cluster randomised trials conducted in low-resource settings: identifying gaps in the

Tiwonge K Mtande, Charles Weijer, Mina C Hosseinipour, Monica Taljaard, Mitch Matoga, Cory E Goldstein, Billy Nyambalo, Nora E Rosenberg

Abstract read
In one paragraph

Article in Journal of medical ethics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Ethics and regulatory complexities posed by a pragmatic clinical trial: a case study from Lilongwe, Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tiwonge K MtandeUniversity of North Carolina Project, Lilongwe, Malawi.
Charles WeijerRotman Institute of Philosophy, University of Western Ontario, London, Ontario, Canada.ORCID 0000-0002-5510-1074
Mina C HosseinipourUniversity of North Carolina Project, Lilongwe, Malawi.
Monica TaljaardOttawa Hospital Research Institute, Ottawa, Ontario, Canada.
Mitch MatogaUniversity of North Carolina Project, Lilongwe, Malawi.
Cory E GoldsteinRotman Institute of Philosophy, Western University, London, Ontario, Canada.
Billy NyambaloResearch Department, Ministry of Health Malawi, Lilongwe, Malawi.
Nora E RosenbergUniversity of North Carolina Project, Lilongwe, Malawi.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Malawi HIV Implementation Research Scientist Training Program (MHIRST)D43TW010060 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MINA CHRISTINE HOSSEINIPOUR, Victor Mwapasa · 2015 to 2026
$3.8M
ARESA - Advancing Research Ethics training in Southern AfricaR25TW008981 · FIC · STELLENBOSCH UNIVERSITY · PI MOODLEY, KEYMANTHRI · 2011 to 2015
$1.2M
Developing and Assessing a Male Engagement Intervention for Option B+ in MalawiR00MH104154 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2017 to 2019
$746k
FIC NIH HHS D43 TW010060FIC NIH HHS R25 TW008981NIAID NIH HHS P30 AI050410NIMH NIH HHS R00 MH104154Wellcome Trust
6 · The paper itself

Abstract

The increasing use of cluster randomised trials in low-resource settings raises unique ethical issues. The

Indexed as

Developing CountriesAnti-HIV AgentsEthics Committees, ResearchEthics, ResearchHealth ResourcesHIV InfectionsHumansInfectious Disease Transmission, VerticalInformed ConsentMalawiRandomized Controlled Trials as TopicResearch DesignResearch SubjectsVulnerable PopulationsAnti-HIV Agentsclinical trialspolicy guidelines/inst. review boards/review cttesresearch ethics

Identifiers

PMID31189724
PMCPMC6613743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.