Evidence map›Paper›PMID 31189715›Full record

ArticleJournal of virology2019

Replication-Defective West Nile Virus with NS1 Deletion as a New Vaccine Platform for Flavivirus.

Na Li, Ya-Nan Zhang, Cheng-Lin Deng, Pei-Yong Shi, Zhi-Ming Yuan, Bo Zhang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Viral Titer Quantification of West Nile Virus by Immunostaining Plaque Assay.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Na LiKey Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Ya-Nan ZhangKey Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Cheng-Lin DengKey Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Pei-Yong ShiUniversity of Texas Medical Branch, Galveston, Texas, USA.
Zhi-Ming YuanKey Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Bo ZhangKey Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China zhangbo@wh.iov.cn.ORCID 0000-0002-8895-3679
Chinese Academy of Sciences · CNThe University of Texas Medical Branch at Galveston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously produced a replication-defective West Nile virus (WNV) lacking NS1 (WNV-ΔNS1) that could propagate at low levels (10

Indexed as

Sequence DeletionAnimalsAntibodies, ViralChlorocebus aethiopsDisease Models, AnimalGene Knockout TechniquesHEK293 CellsHumansImmunizationMiceReceptor, Interferon alpha-betaVero CellsViral Nonstructural ProteinsViral VaccinesVirus ReplicationWest Nile FeverAntibodies, ViralIfnar1 protein, mousenonstructural protein 1, West Nile virusReceptor, Interferon alpha-betaViral Nonstructural ProteinsViral VaccinesflavivirusNS1vaccineWest Nile virus

Identifiers

PMID31189715
PMCPMC6694808
OpenAlexW2950317635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.