Evidence map›Paper›PMID 31189711›Full record

ArticleJournal of virology2019

Porcine Reproductive and Respiratory Syndrome Virus Activates Lipophagy To Facilitate Viral Replication through Downregulation of NDRG1 Expression.

Jiang Wang, Jiao-Yang Liu, Ke-Yu Shao, Ying-Qian Han, Guo-Li Li, Sheng-Li Ming, Bing-Qian Su, Yong-Kun Du, Zhong-Hu Liu, Gai-Ping Zhang and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
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  6. Lycopene Inhibits PRRSV Replication by Suppressing ROS Production.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jiang Wang *College of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Jiao-Yang Liu *College of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Ke-Yu Shao *College of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Ying-Qian HanCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Guo-Li LiCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Sheng-Li MingCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Bing-Qian SuCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Yong-Kun DuCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Zhong-Hu LiuCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Gai-Ping ZhangCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China.
Guo-Yu YangCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China haubiochem@163.com chubeibei_hau@hotmail.com.
Bei-Bei ChuCollege of Animal Sciences and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan Province, People's Republic of China haubiochem@163.com chubeibei_hau@hotmail.com.
Henan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy maintains cellular homeostasis by degrading organelles, proteins, and lipids in lysosomes. Autophagy is involved in the innate and adaptive immune responses to a variety of pathogens. Some viruses can hijack host autophagy to enhance their replication. However, the role of autophagy in porcine reproductive and respiratory syndrome virus (PRRSV) infection is unclear. Here, we show that N-Myc downstream-regulated gene 1 (

Indexed as

Down-RegulationAnimalsAutophagyCell Cycle ProteinsFatty Acids, NonesterifiedHEK293 CellsHumansIntracellular Signaling Peptides and ProteinsMaleN-myc Downstream-Regulated Gene 1 ProteinPhylogenyPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusSwineVirus ReplicationCell Cycle ProteinsFatty Acids, NonesterifiedIntracellular Signaling Peptides and ProteinsN-myc Downstream-Regulated Gene 1 Proteinautophagylipid dropletlipophagyN-Myc downstream-regulated gene 1porcine reproductive and respiratory syndrome virus

Identifiers

PMID31189711
PMCPMC6694807
OpenAlexW2949369903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.