ArticleProceedings of the National Academy of Sciences of the United States of America2019
Second type of criticality in the brain uncovers rich multiple-neuron dynamics.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.
- Is criticality a unified setpoint of brain function?Neuron · 2025Pooled it
- Strong and localized recurrence controls the dimensionality of neural activity across brain areas.Nature neuroscience · 2026Article
- Emergent critical oscillations in motor cortex of Parkinson's patients.bioRxiv : the preprint server for biology · 2026Article
- Online supervised learning of temporal patterns in biological neural networks under feedback control.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Iso-orientation bias of layer 2/3 connections unifies spontaneous, visually and optogenetically driven V1 dynamics.Nature communications · 2026Article
- Article
- Two views of the brain are reconciled by a unifying principle of maximal information processing.bioRxiv : the preprint server for biology · 2025Article
- Continuous Attractor Networks for Laplace Neural Manifolds.Computational brain & behavior · 2025Article
- Brain-wide organization of intrinsic timescales at single-neuron resolution.bioRxiv : the preprint server for biology · 2025Article
- Article
- The cortical critical power law balances energy and information in an optimal fashion.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Phase transitions inArXiv · 2025Article
- Hierarchy of Chaotic Dynamics in Random Modular Networks.Physical review letters · 2025Article
- Measurement effects on critical scaling in neural systems.Frontiers in computational neuroscience · 2025Article
- Critical dynamics in spontaneous EEG predict anesthetic-induced loss of consciousness and perturbational complexity.Communications biology · 2024Article
- The mechanics of correlated variability in segregated cortical excitatory subnetworks.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Low-dimensional criticality embedded in high-dimensional awake brain dynamics.Science advances · 2024Article
- Article
- Psychedelics and disorders of consciousness: the current landscape and the path forward.Neuroscience of consciousness · 2024Article
- Criticality of resting-state EEG predicts perturbational complexity and level of consciousness during anesthesia.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cortical networks that have been found to operate close to a critical point exhibit joint activations of large numbers of neurons. However, in motor cortex of the awake macaque monkey, we observe very different dynamics: massively parallel recordings of 155 single-neuron spiking activities show weak fluctuations on the population level. This a priori suggests that motor cortex operates in a noncritical regime, which in models, has been found to be suboptimal for computational performance. However, here, we show the opposite: The large dispersion of correlations across neurons is the signature of a second critical regime. This regime exhibits a rich dynamical repertoire hidden from macroscopic brain signals but essential for high performance in such concepts as reservoir computing. An analytical link between the eigenvalue spectrum of the dynamics, the heterogeneity of connectivity, and the dispersion of correlations allows us to assess the closeness to the critical point.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.