Evidence map›Paper›PMID 31189578›Full record

ArticleJournal of clinical microbiology2019

Matthew Golden, Meghan O'Donnell, Sheila Lukehart, Paul Swenson, Paul Hovey, Charmie Godornes, Sarah Romano, Damon Getman

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

  1. Detection ofMicrobiology spectrum · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Update on syphilis diagnostics.Current opinion in infectious diseases · 2025
    Review
  10. Article
  11. Article
  12. An Update on the Status of Direct Testing forJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Review
  13. Article
  14. CDC Laboratory Recommendations for Syphilis Testing, United States, 2024.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2024
    Article
  15. Serologic correlation of a research-use-onlyJournal of clinical microbiology · 2024
    Article
  16. Timely Diagnosis of Incubating Syphilis Infections Using Treponema pallidum Transcription-Mediated Amplification Assay.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Matthew GoldenDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA golden@uw.edu.
Meghan O'DonnellHologic, Inc., San Diego, California, USA.
Sheila LukehartDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Paul SwensonPublic Health-Seattle & King County, Seattle, Washington, USA.
Paul HoveyHologic, Inc., San Diego, California, USA.
Charmie GodornesDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Sarah RomanoUniversity of Washington School of Public Health, Seattle, Washington, USA.
Damon GetmanHologic, Inc., San Diego, California, USA.
University of Washington · USHologic (United States) · USPublic Health – Seattle & King County · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syphilis rates in much of the world are now at their highest levels in almost three decades, and new approaches to controlling syphilis, including diagnostic tests with shorter window periods, are urgently needed. We compared the sensitivity of syphilis serological testing using the rapid plasma reagin (RPR) test with that of the combination of serological testing and an experimental 23S rRNA

Indexed as

Homosexuality, MaleAdolescentAdultAgedCross-Sectional StudiesHumansMaleMass ScreeningMiddle AgedNucleic Acid Amplification TechniquesPharynxRectumRNA, Ribosomal, 23SSensitivity and SpecificitySyphilisSyphilis SerodiagnosisRNA, Ribosomal, 23Sdiagnosticsnucleic acid amplificationsyphilisTreponema pallidum

Identifiers

PMID31189578
PMCPMC6663910
OpenAlexW2964294788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.