Evidence map›Paper›PMID 31189527›Full record

ArticleBlood advances2019

CRISPR genome editing of murine hematopoietic stem cells to create

Soumya Sundara Rajan, Lingxiao Li, Mercedes F Kweh, Kranthi Kunkalla, Amit Dipak Amin, Nitin K Agarwal, Francisco Vega, Jonathan H Schatz

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Soumya Sundara RajanSheila and David Fuente Graduate Program in Cancer Biology.
Lingxiao LiSylvester Comprehensive Cancer Center.
Mercedes F KwehSylvester Comprehensive Cancer Center.
Kranthi KunkallaSylvester Comprehensive Cancer Center.
Amit Dipak AminSylvester Comprehensive Cancer Center.
Nitin K AgarwalSylvester Comprehensive Cancer Center.
Francisco VegaSylvester Comprehensive Cancer Center.ORCID 0000-0001-5956-452X
Jonathan H SchatzSylvester Comprehensive Cancer Center.ORCID 0000-0003-1842-228X
Sylvester Comprehensive Cancer Center · USUniversity of Miami · US

Funding

A New Treatment Paradigm for ALK-Driven Cancers Exploiting Oncogene OverdoseR01CA190696 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SCHATZ, JONATHAN H · 2014 to 2018
$1.5M
Cancer Epigenetics Training ProgramT32CA217835 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FIGUEROA, MARIA EUGENIA, MOREY, LLUIS · 2018 to 2022
$1.3M
NCI NIH HHS R01 CA190696NCI NIH HHS T32 CA217835
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAnaplastic Lymphoma KinaseAnimalsBone MarrowCell Culture TechniquesClustered Regularly Interspaced Short Palindromic RepeatsFetal Tissue TransplantationFetusGene EditingHematopoietic Stem CellsHematopoietic Stem Cell TransplantationHumansLiverLymphoma, T-CellMiceMice, Inbred C57BLAlk protein, mouseAnaplastic Lymphoma KinaseNPM1 protein, humanNpm1 protein, mouseNuclear ProteinsNucleophosminOncogene Proteins, FusionReceptor Protein-Tyrosine Kinases

Identifiers

PMID31189527
PMCPMC6595257
OpenAlexW2952288012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.