Evidence map›Paper›PMID 31189482›Full record

ArticleBMC biology2019

The impact of skin care products on skin chemistry and microbiome dynamics.

Amina Bouslimani, Ricardo da Silva, Tomasz Kosciolek, Stefan Janssen, Chris Callewaert, Amnon Amir, Kathleen Dorrestein, Alexey V Melnik, Livia S Zaramela, Ji-Nu Kim and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. The cutaneous microbiome as a dynamic photoprotective interface against solar radiation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Importance of human microbiome: an update.Frontiers in microbiomes · 2026
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Amina BouslimaniCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, USA.
Ricardo da SilvaCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, USA.
Tomasz KosciolekDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Stefan JanssenDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Chris CallewaertDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Amnon AmirDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Kathleen DorresteinCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, USA.
Alexey V MelnikCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, USA.
Livia S ZaramelaDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Ji-Nu KimDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Gregory HumphreyDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Tara SchwartzDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Karenina SandersDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Caitriona BrennanDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Tal Luzzatto-KnaanCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, USA.
Gail AckermannDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Daniel McDonaldDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Karsten ZenglerDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA.
Rob KnightDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, 92037, USA. rknight@ucsd.edu.
Pieter C DorresteinCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, USA. pdorrestein@ucsd.edu.

Funding

Transcriptional response of a skin microbiome transplantR21AR071731 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZENGLER, KARSTEN B · 2017 to 2017
$341k
NIAMS NIH HHS R21 AR071731
6 · The paper itself

Abstract

backgroundUse of skin personal care products on a regular basis is nearly ubiquitous, but their effects on molecular and microbial diversity of the skin are unknown. We evaluated the impact of four beauty products (a facial lotion, a moisturizer, a foot powder, and a deodorant) on 11 volunteers over 9 weeks.

resultsMass spectrometry and 16S rRNA inventories of the skin revealed decreases in chemical as well as in bacterial and archaeal diversity on halting deodorant use. Specific compounds from beauty products used before the study remain detectable with half-lives of 0.5-1.9 weeks. The deodorant and foot powder increased molecular, bacterial, and archaeal diversity, while arm and face lotions had little effect on bacterial and archaeal but increased chemical diversity. Personal care product effects last for weeks and produce highly individualized responses, including alterations in steroid and pheromone levels and in bacterial and archaeal ecosystem structure and dynamics.

conclusionsThese findings may lead to next-generation precision beauty products and therapies for skin disorders.

Indexed as

AdultCosmeticsFemaleHumansMaleMicrobiotaSkinSkin CareCosmetics16S rRNA sequencingBacteriaMass spectrometryMetabolomicsSkinSkin care products

Identifiers

PMID31189482
PMCPMC6560912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.