Evidence map›Paper›PMID 31188909›Full record

ReviewClinics (Sao Paulo, Brazil)2019

Screening of Strongyloides infection using an ELISA test in transplant candidates.

Beatriz Toledo, Marcelo A Corral, Dirce Mary C L Meisel, Maiara Gottardi, Edson Abdala, Silvia F Costa, Lígia Camera Pierrotti, Susana A Z Lescano, Elenice M N Gonçalves, Vera L P Castilho and 3 more

Abstract readReview
In one paragraph

Review in Clinics (Sao Paulo, Brazil), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Evaluation of Each ThreeMicroorganisms · 2025
    Article
  3. Strongyloidiasis.Nature reviews. Disease primers · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Strongyloides Superinfection After Liver Transplantion.Digestive diseases and sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Beatriz ToledoLaboratorio de Investigacao Medica (LIM/06 - Laboratorio de Imunopatologia da esquistossomose), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Marcelo A CorralLaboratorio de Investigacao Medica (LIM/06 - Laboratorio de Imunopatologia da esquistossomose), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Dirce Mary C L MeiselLaboratorio de Investigacao Medica (LIM/06 - Laboratorio de Imunopatologia da esquistossomose), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Maiara GottardiLaboratorio de Investigacao Medica (LIM/06 - Laboratorio de Imunopatologia da esquistossomose), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Edson AbdalaHospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0003-0765-6654
Silvia F CostaHospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Lígia Camera PierrottiHospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0002-0216-3028
Susana A Z LescanoLaboratorio de Investigacao Medica (LIM/06 - Laboratorio de Imunopatologia da esquistossomose), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Elenice M N GonçalvesSecao de Parasitologia da Divisao de Laboratorio Central, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Vera L P CastilhoSecao de Parasitologia da Divisao de Laboratorio Central, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Pedro P ChieffiFaculdade de Ciencias Medicas, Santa Casa, Sao Paulo, SP, BR.
Ronaldo C B GryschekLaboratorio de Investigacao Medica (LIM/06 - Laboratorio de Imunopatologia da esquistossomose), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Fabiana M PaulaLaboratorio de Investigacao Medica (LIM/06 - Laboratorio de Imunopatologia da esquistossomose), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0003-3343-0149

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHyperinfection or disseminated strongyloidiasis has been frequently reported after transplants and is related to high mortality. This study aimed to screen for strongyloidiasis using serological diagnoses in transplant candidates.

methodsAn ELISA test was performed with filariform larvae of Strongyloides venezuelensis as a source of antigen.

resultsIn the serum from transplant candidates, anti-Strongyloides IgG antibodies were detected in 35/150 (23.3%) samples by soluble fractions in phosphate buffered saline (PBS), 31/150 (20.7%) samples by soluble fractions in Tris-HCl, 27/150 (18.0%) samples by membrane fractions in PBS and 22/150 (14.7%) samples by membrane fractions in Tris-HCl.

conclusionsThe present results suggest the ELISA test, ideally using soluble fractions of filariform larvae S. venezuelensis in PBS, as an additional strategy for the diagnosis of strongyloidiasis in transplant candidates.

Indexed as

Organ TransplantationAdolescentAdultAnimalsAntibodies, HelminthAntigens, HelminthBiomarkersChildEnzyme-Linked Immunosorbent AssayFemaleHumansImmunocompromised HostImmunoglobulin GMaleMass ScreeningMiddle AgedAntibodies, HelminthAntigens, HelminthBiomarkersImmunoglobulin G

Identifiers

PMID31188909
PMCPMC6537660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.