Evidence map›Paper›PMID 31188709›Full record

ArticleMolecular biology of the cell2019

Specialized eRpL22 paralogue-specific ribosomes regulate specific mRNA translation in spermatogenesis in

Catherine M Mageeney, Vassie C Ware

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. RiboScreenBiomedicines · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Specialized ribosomes: integrating new insights and current challenges.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  9. Ribosomal protein paralogues in ribosome specialization.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  10. Building a case for 'functional identity fraud' in eRpL22 paralogue-specific ribosomes inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  11. Article
  12. Ribosome Structural Changes Dynamically Affect Ribosome Function.International journal of molecular sciences · 2024
    Review
  13. A dual ribosomal system in the zebrafish soma and germline.bioRxiv : the preprint server for biology · 2024
    Article
  14. Article
  15. Ribosome Specialization in Protozoa Parasites.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Article
  18. Comparative Ubiquitome Analysis Reveals Deubiquitinating Effects Induced byInternational journal of molecular sciences · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Catherine M MageeneyDepartment of Biological Sciences, Lehigh University, Bethlehem, PA 18015.
Vassie C WareDepartment of Biological Sciences, Lehigh University, Bethlehem, PA 18015.
Lehigh University · US

Funding

Exploring Mechanisms of Specialized Ribosome Function in the Male Germline in Drosophila MelanogasterR15GM132889 · NIGMS · LEHIGH UNIVERSITY · PI WARE, VASSIE C. · 2019 to 2019
$457k
NIGMS NIH HHS R15 GM132889
6 · The paper itself

Abstract

The functional significance of ribosome heterogeneity in development and differentiation is relatively unexplored. We present the first in vivo evidence of ribosome heterogeneity playing a role in specific mRNA translation in a multicellular eukaryote. Eukaryotic-specific ribosomal protein paralogues eRpL22 and eRpL22-like are essential in development and required for sperm maturation and fertility in

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsFertilityGerm CellsMalePolyribosomesProtein BiosynthesisRibosomal ProteinsRibosomesRNA-Binding ProteinsRNA, MessengerSpermatogenesisTestisDrosophila ProteinsRibosomal ProteinsRNA-Binding ProteinsRNA, MessengerRpl22-like protein, DrosophilaRpL22 protein, Drosophila

Identifiers

PMID31188709
PMCPMC6743460
OpenAlexW2951614727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.