Evidence map›Paper›PMID 31188627›Full record

ArticleBiopreservation and biobanking2019

The Utilization of Biospecimens: Impact of the Choice of Biobanking Model.

William E Grizzle, Marianna J Bledsoe, Sameer Al Diffalha, Dennis Otali, Katherine C Sexton

Abstract read
In one paragraph

Article in Biopreservation and biobanking, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Use of Human Tissues for Research: What Investigators Need to Know.Alternatives to laboratory animals : ATLA · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

William E Grizzle1 Department of Pathology and the Comprehensive Cancer Center, The University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Marianna J Bledsoe2 Independent Consultant, Deputy Editor, Biopreservation and Biobanking, Silver Spring, Maryland.
Sameer Al Diffalha1 Department of Pathology and the Comprehensive Cancer Center, The University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Dennis Otali1 Department of Pathology and the Comprehensive Cancer Center, The University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Katherine C Sexton1 Department of Pathology and the Comprehensive Cancer Center, The University of Alabama at Birmingham (UAB), Birmingham, Alabama.

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Collaborative Human Tissue NetworkUM1CA183728 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GRIZZLE, WILLIAM E. · 2014 to 2018
$3.7M
NCI NIH HHS P30 CA013148NCI NIH HHS UM1 CA183728
6 · The paper itself

Abstract

The term research "biobank" is one of multiple names (e.g., bioresource, biorepository,) used to designate an entity that receives, collects, processes, stores, and/or distributes biospecimens or other biospecimen-related products (e.g., data) to support research. There are multiple organizational models of biobanking used by bioresources, but the primary goal of all bioresources should not be simply to collect biospecimens, but ultimately to distribute almost all collected biospecimens and/or data to support scientific research; bioresources should serve as "biodistributors" rather than "biovaults." The appropriate choice of model is the first step in ensuring optimal biospecimen utilization by a bioresource. This article discusses some of the different models that may be used alone or in combination by a bioresource providing biospecimens for research; it describes the factors affecting the choice of the most appropriate model or models, the advantages and disadvantages of the various models, and a discussion of the impact of the choice of the model on biospecimen utilization. Frequently, problems with biospecimen utilization are not caused by any single model, but rather a mismatch between the choice of model and goals of the bioresource, and/or problems with the subsequent design, goals, operations, and management of the bioresource after a model is selected.

Indexed as

Biological Specimen BanksFacilities and Services UtilizationModels, TheoreticalClinical Trials as TopicHumansbiobankbiodistributorbiorepositorybioresourcebiospecimenprospectiveutilization

Identifiers

PMID31188627
PMCPMC7061300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.