Evidence map›Paper›PMID 31188564›Full record

ArticleACS nano2019

Increasing the Efficacy of Stem Cell Therapy via Triple-Function Inorganic Nanoparticles.

Fang Chen, Eric Ruike Zhao, Ghanim Hableel, Tao Hu, Taeho Kim, Jingting Li, Natalia Isabel Gonzalez-Pech, David J Cheng, Jeanne E Lemaster, Yijun Xie and 3 more

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
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  9. Review
  10. Silica-Based Advanced Nanoparticles For Treating Ischemic Disease.Tissue engineering and regenerative medicine · 2023
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Eric Ruike Zhao
Ghanim Hableel
Tao HuSchool of Materials Science and Engineering , Central South University , Changsha 410083 , China.
Taeho KimDepartment of Biomedical Engineering, Institute of Quantitative Health Science and Engineering , Michigan State University , 775 Woodlot Drive , East Lansing , Michigan 48824 , United States.ORCID 0000-0002-7500-8918
Jingting Li
Natalia Isabel Gonzalez-PechORCID 0000-0003-4189-850X
David J Cheng
Jeanne E Lemaster
Yijun Xie
Vicki H GrassianScripps Institution of Oceanography, San Diego , 9500 Gilman Drive , La Jolla , California 92093 , United States.ORCID 0000-0001-5052-0045
George L Sen
University of California San Diego · USCentral South University · CNScripps Institution of Oceanography · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9M
Signaling GatewayR01GM078005 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUBRAMANIAM, SHANKAR · 2006 to 2012
$3.7M
Therapeutic Drug Monitoring with a Wearable Ultrasound-based SensorDP2HL137187 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2016 to 2019
$2.7M
Cancer Researchers in Nanotechnology (CRIN)T32CA153915 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KUMMEL, ANDREW CLYDE, ZHANG, DONG-ER · 2017 to 2021
$994k
A Therapeutic Tool for Ultrasound-Guided Stem Cell TherapyR00HL117048 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2015 to 2017
$747k
MR Solutions Benchtop Cryogen Free Superconducting 1.5T/3.0T Rodent MR ScannerS10OD018225 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VERA, DAVID R. · 2015 to 2015
$600k
Vevo LAZR Photoacoustic Imaging SystemS10OD021821 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALL, DAVID J · 2016 to 2016
$594k
JEOL JEM-1400Plus Transmission Electron MicroscopeS10OD023527 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FARQUHAR, MARILYN GIST · 2017 to 2017
$579k
NCI NIH HHS P30 CA023100NCI NIH HHS T32 CA153915NHLBI NIH HHS DP2 HL137187NHLBI NIH HHS R00 HL117048NIGMS NIH HHS R01 GM078005NIH HHS S10 OD018225NIH HHS S10 OD021821NIH HHS S10 OD023527
6 · The paper itself

Abstract

Stem cell therapy in heart disease is challenged by mis-injection, poor survival, and low cell retention. Here, we describe a biocompatible multifunctional silica-iron oxide nanoparticle to help solve these issues. The nanoparticles were made via an in situ growth of Fe

Indexed as

AnimalsCells, CulturedContrast MediaDrug LiberationFerric CompoundsHumansInsulin-Like Growth Factor IMagnetic Resonance ImagingMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMiceMice, Inbred C57BLMyocardial InfarctionNanoparticlesSilicon DioxideTheranostic NanomedicineContrast MediaFerric Compoundsferric oxideInsulin-Like Growth Factor ISilicon Dioxidecell manipulationcontrast agentsmesoporous silica−iron oxide nanoparticlesstem cell therapytheranostic nanoparticles

Identifiers

PMID31188564
PMCPMC8106804
OpenAlexW2951963985

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.