ArticleHuman brain mapping2019
Abnormalities of hippocampal shape and subfield volumes in medication-free patients with obsessive-compulsive disorder.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Shape analysis of subcortical structures in obsessive-compulsive disorder and the relationship with comorbid anxiety, depression, and medication use: A meta-analysis by the OCD Brain Imaging Consortium.Brain and behavior · 2022Pooled it
- Review
- Structural plasticity of the contralesional hippocampus and its subfields in patients with glioma.European radiology · 2023Article
- Subcortical shape in pediatric and adult obsessive-compulsive disorder.Depression and anxiety · 2022Article
- Hippocampal adaptation to high altitude: a neuroanatomic profile of hippocampal subfields in Tibetans and acclimatized Han Chinese residents.Frontiers in neuroanatomy · 2022Article
- FreeSurfer-based segmentation of hippocampal subfields: A review of methods and applications, with a novel quality control procedure for ENIGMA studies and other collaborative efforts.Human brain mapping · 2022Review
- Alterations in hippocampal subfield and amygdala subregion volumes in posttraumatic subjects with and without posttraumatic stress disorder.Human brain mapping · 2021Article
- Obsessive-compulsive disorder in children and adolescents: epidemiology, diagnosis and management.Translational pediatrics · 2020Review
- Maintained Visual-, Auditory-, and Multisensory-Guided Associative Learning Functions in Children With Obsessive-Compulsive Disorder.Frontiers in psychiatry · 2020Article
- Abnormalities of hippocampal shape and subfield volumes in medication-free patients with obsessive-compulsive disorder.Human brain mapping · 2019Article
- Hippocampal and amygdala subfield volumes in obsessive-compulsive disorder by medication status.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
In this study, we sought to identify alterations of hippocampal shape and subfield volumes in a relatively large sample of medication-free obsessive-compulsive disorder (OCD) patients without comorbid depression. 3D T1-weighted Magnetic Resonance Imaging scans were collected from 81 medication-free OCD patients and 95 age- and sex-matched healthy controls (HC). Total hippocampal volume and volume of eight bilateral subfields were measured using FreeSurfer software. Subregional shape deformity was examined via FSL software. Volumetric and shape differences between groups and correlations with OCD symptoms were examined. The volume of right hippocampus was significantly reduced in OCD patients (p = .001, η
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.