Evidence map›Paper›PMID 31188077›Full record

ArticleZebrafish2019

Polyketide Synthase Plays a Conserved Role in Otolith Formation.

Mi-Sun Lee, Julien Philippe, Nicholas Katsanis, Weibin Zhou

Open access · greenAbstract read
In one paragraph

Article in Zebrafish, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Cilia in the developing zebrafish ear.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mi-Sun Lee1Department of Biological Chemistry, Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, Michigan.
Julien Philippe2Center for Human Disease Modeling, Division of Nephrology, Duke University School of Medicine, Durham, North Carolina.
Nicholas Katsanis2Center for Human Disease Modeling, Division of Nephrology, Duke University School of Medicine, Durham, North Carolina.
Weibin Zhou2Center for Human Disease Modeling, Division of Nephrology, Duke University School of Medicine, Durham, North Carolina.
Duke University · USUniversity of Michigan · US

Funding

Research BaseP30DK090868 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI WATNICK, TERRY J · 2010 to 2019
$11.1M
NIDDK NIH HHS P30 DK090868
6 · The paper itself

Abstract

Otoliths (ear stones) are biomineralized complexes essential for the balancing and hearing function of the inner ears in fish. Their formation is controlled by a genetically programmed biological process that is yet to be defined. We have isolated and characterized a spontaneous genetic mutant zebrafish with a complete absence of otoliths, named

Indexed as

AnimalsEmbryonic DevelopmentOrganogenesisOryziasOtolithic MembranePolyketide SynthasesZebrafishZebrafish Proteinspks1 protein, zebrafishPolyketide SynthasesZebrafish Proteinsbalancingearhearingotolith

Identifiers

PMID31188077
PMCPMC6685216
OpenAlexW2951112212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.