Evidence map›Paper›PMID 31187898›Full record

ReviewComprehensive Physiology2019

Nitric Oxide and Hydrogen Sulfide Regulation of Ischemic Vascular Growth and Remodeling.

Saranya Rajendran, Xinggui Shen, John Glawe, Gopi K Kolluru, Christopher G Kevil

Abstract readReview
In one paragraph

Review in Comprehensive Physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Review
  3. Protective effects ofToxicology reports · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Functionalized MoSJournal of nanobiotechnology · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Saranya RajendranDepartments of Pathology, LSU Health Sciences Center, Shreveport.
Xinggui ShenDepartments of Pathology, LSU Health Sciences Center, Shreveport.
John GlaweDepartments of Pathology, LSU Health Sciences Center, Shreveport.
Gopi K KolluruDepartments of Pathology, LSU Health Sciences Center, Shreveport.
Christopher G KevilDepartments of Pathology, LSU Health Sciences Center, Shreveport.
Louisiana State University Health Sciences Center Shreveport · US

Funding

Stress Exacerbates Myocardial Ischemic Injury by Blocking Estrogen's Antidoxidant Protection in the Female HeartP20GM121307 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Christopher G Kevil · 2018 to 2026
$23.6M
Hydrogen sulfide and vascular remodelingR01HL113303 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI KEVIL, CHRISTOPHER G · 2012 to 2016
$1.8M
NHLBI NIH HHS R01 HL113303NIGMS NIH HHS P20 GM121307
6 · The paper itself

Abstract

Ischemic vascular remodeling occurs in response to stenosis or arterial occlusion leading to a change in blood flow and tissue perfusion. Altered blood flow elicits a cascade of molecular and cellular physiological responses leading to vascular remodeling of the macro- and micro-circulation. Although cellular mechanisms of vascular remodeling such as arteriogenesis and angiogenesis have been studied, therapeutic approaches in these areas have had limited success due to the complexity and heterogeneous constellation of molecular signaling events regulating these processes. Understanding central molecular players of vascular remodeling should lead to a deeper understanding of this response and aid in the development of novel therapeutic strategies. Hydrogen sulfide (H

Indexed as

Cardiovascular DiseasesHumansHydrogen SulfideIntercellular Signaling Peptides and ProteinsIschemiaMutationNeovascularization, PathologicNeovascularization, PhysiologicNitric OxideSignal TransductionVascular RemodelingHydrogen SulfideIntercellular Signaling Peptides and ProteinsNitric Oxide

Identifiers

PMID31187898
PMCPMC6938731
OpenAlexW2952867094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.