Evidence map›Paper›PMID 31187563›Full record

ReviewThoracic cancer2019

ACTH-producing thymic neuroendocrine tumor initially presenting as psychosis: A case report and literature review.

Taiki Okumura, Shohei Takayama, Shin-Ichi Nishio, Takahiro Miyakoshi, Takuro Noguchi, Takashi Kobayashi, Toshirou Fukushima, Nodoka Sekiguchi, Toshiaki Otsuki, Mitsuhisa Komatsu and 1 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Thoracic cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Taiki OkumuraSecond Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Shohei TakayamaFourth Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Shin-Ichi NishioFourth Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Takahiro MiyakoshiFourth Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Takuro NoguchiDepartment of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Takashi KobayashiDepartment of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Toshirou FukushimaDepartment of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Nodoka SekiguchiDepartment of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Toshiaki OtsukiDepartment of Central Laboratory, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Mitsuhisa KomatsuFourth Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Tomonobu KoizumiDepartment of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.ORCID 0000-0002-5182-0960
Shinshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 32-year-old woman was referred to our hospital because of severe psychosis and was found to have an ectopic ACTH-producing thymic neuroendocrine tumor. Laboratory data revealed an elevated serum cortisol and plasma ACTH level, hypokalemia, and metabolic alkalosis. Chest computed tomography (CT) revealed an anterior mediastinal mass and multiple pulmonary nodules. As the patient was unable to communicate because of her consciousness disturbance, she was managed with artificial ventilation and deep sedation. Metyrapone and potassium supplementation were administered, and steroid psychosis gradually improved. Thoracic surgery was performed and the histopathological diagnosis was thymic neuroendocrine tumor with positive anti-ACTH immunohistochemical staining. Here we present details of the case and review the literature.

Indexed as

Adrenocorticotropic HormoneAdultFemaleHumansMetyraponeMultiple Pulmonary NodulesNeuroendocrine TumorsPotassiumPsychotic DisordersThymus NeoplasmsTomography, X-Ray ComputedAdrenocorticotropic HormoneMetyraponePotassiumMediastinal carcinoidmental disorderneuroendocrine carcinomapulmonary metastasissevere psychosis

Identifiers

PMID31187563
PMCPMC6610259
OpenAlexW2952175741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.