Evidence map›Paper›PMID 31187538›Full record

ArticleJournal of applied clinical medical physics2019

Evaluation of setup and intrafraction motion for surface guided whole-breast cancer radiotherapy.

Sandra Helene Hattel, Peter Andreas Andersen, Isak Hannes Wahlstedt, Sidsel Damkjaer, Arpit Saini, Jakob Borup Thomsen

Abstract readEvaluation Study
In one paragraph

Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Trial
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  6. Operational assessment of tattooless breast radiotherapy using AlignRT surface guidance.Technical innovations & patient support in radiation oncology · 2025
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  8. Use of surface tracking recordings to identify pitfalls during surface-guided radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandra Helene HattelDepartment of Electrical Engineering, Technical University of Denmark, Lyngby, Denmark.
Peter Andreas AndersenDepartment of Oncology, Section of Radiotherapy, Rigshospitalet, Copenhagen, Denmark.
Isak Hannes WahlstedtDepartment of Oncology, Section of Radiotherapy, Rigshospitalet, Copenhagen, Denmark.
Sidsel DamkjaerDepartment of Clinical Oncology and Radiotherapy, Zealand University Hospital, Naestved, Denmark.
Arpit SainiDepartment of Clinical Oncology and Radiotherapy, Zealand University Hospital, Naestved, Denmark.
Jakob Borup ThomsenDepartment of Oncology, Section of Radiotherapy, Rigshospitalet, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surface Guided Radiotherapy (SGRT) is a relatively new technique for positioning patients and for monitoring patient movement during treatment. SGRT is completely non-invasive since it uses visible light for determining the position of the patient surface. A reduction in daily imaging for patient setup is possible if the accuracy of SGRT is comparable to imaging. It allows for monitoring of intrafraction motion and the radiation beam can be held beyond a certain threshold resulting in a more accurate irradiation. The purpose of this study was to investigate setup uncertainty and the intrafraction motion in non-gated whole breast cancer radiotherapy treatment using an integrated implementation of AlignRT (OSMS) system as SGRT. In initial setup, SGRT was compared to three-point setup using tattoos on the patient and orthogonal kV imaging. For the investigation of intrafraction motion, OSMS monitored the patient with six degrees of freedom during treatment. Using three-point setup resulted in a setup root-mean-square error from the isocenter of 5.4 mm. This was improved to 4.2 mm using OSMS. For the translational directions, OSMS showed improvements in the lateral direction (P = 0.0009, Wilcoxon rank-sum), but for the longitudinal direction and rotation it was not possible to show improvements (P = 0.96 and P = 0.46, respectively). The vertical direction proved more accurate for three-point setup than OSMS (P = 0.000004). Intrafraction motion was very limited with a translational median of 1.1 mm from the isocenter. While OSMS showed marked improvements over laser and tattoo setup, the system did not prove accurate enough to replace the daily orthogonal kV images aligned to bony anatomy.

Indexed as

Patient PositioningPhantoms, ImagingAgedAged, 80 and overBreast NeoplasmsCone-Beam Computed TomographyFemaleHumansImage Processing, Computer-AssistedImmobilizationMiddle AgedMovementPrognosisRadiotherapy DosageRadiotherapy, Image-GuidedRadiotherapy, Intensity-Modulatedbreast cancerintrafractional movementoptical surface imagingsetup accuracysurface guided radiotherapy

Identifiers

PMID31187538
PMCPMC6560238

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.