Evidence map›Paper›PMID 31187485›Full record

ArticleDevelopmental psychobiology2019

Neonatal EEG linked to individual differences in socioemotional outcomes and autism risk in toddlers.

Natalie H Brito, Amy J Elliott, Joseph R Isler, Cynthia Rodriguez, Christa Friedrich, Lauren C Shuffrey, William P Fifer

Open access · greenAbstract read
In one paragraph

Article in Developmental psychobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. How the Brain Interprets Pain in Autistic People: Does Sex Matter?European journal of pain (London, England) · 2026
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  14. Rodent Models for ASD Biomarker Development.Advances in neurobiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Natalie H BritoDepartment of Applied Psychology, New York University, New York, New York.ORCID 0000-0003-1016-0094
Amy J ElliottCenter for Pediatric & Community Research, Avera Research Institute, Sioux Falls, South Dakota.
Joseph R IslerDepartment of Pediatrics, Columbia University Medical Center, New York, New York.
Cynthia RodriguezDivision of Developmental Neuroscience, New York State Psychiatric Institute, New York, New York.
Christa FriedrichCenter for Pediatric & Community Research, Avera Research Institute, Sioux Falls, South Dakota.
Lauren C ShuffreyDivision of Developmental Neuroscience, New York State Psychiatric Institute, New York, New York.
William P FiferDepartment of Pediatrics, Columbia University Medical Center, New York, New York.
Columbia University Irving Medical Center · USUniversity of South Dakota · USNew York Psychoanalytic Society and Institute · USNew York University · US

Funding

Environmental Influences on Childhood Outcomes in the Northern Plains Safe Passage Study CohortsUH3OD023279 · OD · AVERA MCKENNAN · PI Amy J Elliott, Christine W Hockett · 2018 to 2026
$31.7M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Environmental Influences on Child Health Outcomes in the Northern Plains Safe Passage Study CohortUG3OD023279 · OD · SANFORD RESEARCH/USD · PI ELLIOTT, AMY J, HOCKETT, CHRISTINE W · 2016 to 2024
$17.5M
Prenatal Alcohol in Sudden Infant Death Syndrome and Stillbirth (PASS) NetworkU01HD045935 · NICHD · UNIVERSITY OF SOUTH DAKOTA · PI ELLIOTT, AMY J · 2003 to 2015
$16.9M
Translational Research Training in Child PsychiatryT32MH016434 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Cristiane S. Duarte, Kate Dimond Fitzgerald · 1985 to 2026
$10.9M
Prenatal Alcohol in Sudden Infant Death Syndrome and Stillbirth (PASS) NetworkU01HD055155 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FIFER, WILLIAM P., MYERS, MICHAEL MORGAN · 2006 to 2015
$7.1M
Perinatal Assessment of At-Risk PopulationsR37HD032774 · NICHD · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI FIFER, WILLIAM P. · 2006 to 2015
$4.2M
Contributions of SES and Bilingualism on Early Cognitive DevelopmentR00HD086255 · NICHD · NEW YORK UNIVERSITY · PI BRITO, NATALIE HIROMI · 2017 to 2019
$730k
NCATS NIH HHS UL1 TR000040NICHD NIH HHS R00 HD086255NICHD NIH HHS R37 HD032774NICHD NIH HHS U01 HD045935NICHD NIH HHS U01 HD055155NIH HHS UH3 OD023279NIMH NIH HHS T32 MH016434
6 · The paper itself

Abstract

Research using electroencephalography (EEG) as a measure of brain function and maturation has demonstrated links between cortical activity and cognitive processes during infancy and early childhood. The current study examines whether neonatal EEG is correlated with later atypical socioemotional behaviors or neurocognitive delays. Parental report developmental assessments were administered to families with children ages 24 to 36 months who had previously participated in a neonatal EEG study (N = 129). Significant associations were found between neonatal EEG (higher frequencies in the frontal polar, temporal, and parietal brain regions) and BITSEA ASD risk scores. Infants with lower EEG power in these brain areas were more likely to have higher risk of socioemotional problems. When examining sex differences, significant links were found for males but not for females. These results demonstrate some promising associations between early neural biomarkers and later risk for atypical behaviors, which may shape early neurobehavioral development and could lead to earlier identification and intervention.

Indexed as

ElectroencephalographyIndividualitySocial SkillsAutism Spectrum DisorderBiomarkersCerebral CortexChild DevelopmentChild, PreschoolEmotionsFemaleHumansInfant, NewbornLongitudinal StudiesMaleSex FactorsBiomarkersautism riskBITSEAbrain activitycognitionEEGsocioemotional development

Identifiers

PMID31187485
PMCPMC6874708
OpenAlexW2952241844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.