ArticleMedical & biological engineering & computing2019
Repolarization variability independent of heart rate during sympathetic activation elicited by head-up tilt.
Article in Medical & biological engineering & computing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Short-Term Beat-to-Beat QT Variability Appears Influenced More Strongly by Recording Quality Than by Beat-to-Beat RR Variability.Frontiers in physiology · 2022Article
- Improvement of Sympathovagal Balance by Regular Exercise May Counteract the Ageing Process. A Study by the Analysis of QT Variability.Frontiers in physiology · 2022Article
- Heart Rate Asymmetry Analysis During Head-Up Tilt Test in Healthy Men.Frontiers in physiology · 2021Article
- Sex and Rate Change Differences in QT/RR Hysteresis in Healthy Subjects.Frontiers in physiology · 2021Article
- Multivariate and Multiscale Complexity of Long-Range Correlated Cardiovascular and Respiratory Variability Series.Entropy (Basel, Switzerland) · 2020Article
- Autonomic Control of the Heart and Its Clinical Impact. A Personal Perspective.Frontiers in physiology · 2020Article
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
The fraction of repolarization variability independent of RR interval variability is of clinical interest. It has been linked to direct autonomic nervous system (ANS) regulation of the ventricles in healthy subjects and seems to reflect the instability of the ventricular repolarization process in heart disease. In this study, we sought to identify repolarization measures that best reflect the sympathetic influences on the ventricles independent of the RR interval. ECG was recorded in 46 young subjects during supine and then following 45 degrees head-up tilt. RR intervals and five repolarization features (QTend, QTpeak, RTend, RTpeak, and TpTe) were extracted from the ECG recordings. Repolarization variability was separated into RR-dependent and RR-independent variability using parametric spectral analysis. Results show that LF power of TpTe is independent of RR in both supine and tilt, while the LF power of QTend and RTend independent of RR and respiration increases following tilt. We conclude that TpTe is independent of RR and is highly affected by respiration. QTend and RTend LF power might reflect the sympathetic influences on the ventricles elicited by tilt. Graphical abstract.
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Registered trials
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