Evidence map›Paper›PMID 31187382›Full record

ReviewThe protein journal2019

The Principles of Protein Targeting and Transport Across Cell Membranes.

Yuanyuan Chen, Sri Karthika Shanmugam, Ross E Dalbey

Abstract readReview
PubMed Publisher
In one paragraph

Review in The protein journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. YeastbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. A novel polysaccharide in the envelope ofJournal of bacteriology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. The Cytoplasmic Domains ofFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yuanyuan ChenDepartment of Chemistry and Biochemistry, Ohio State University, Columbus, OH, USA.
Sri Karthika ShanmugamDepartment of Chemistry and Biochemistry, Ohio State University, Columbus, OH, USA.
Ross E DalbeyDepartment of Chemistry and Biochemistry, Ohio State University, Columbus, OH, USA. dalbey.1@osu.edu.
The Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The past several decades have witnessed tremendous growth in the protein targeting, transport and translocation field. Major advances were made during this time period. Now the molecular details of the targeting factors, receptors and the membrane channels that were envisioned in Blobel's Signal Hypothesis in the 1970s have been revealed by powerful structural methods. It is evident that there is a myriad of cytosolic and membrane associated systems that accurately sort and target newly synthesized proteins to their correct membrane translocases for membrane insertion or protein translocation. Here we will describe the common principles for protein transport in prokaryotes and eukaryotes.

Indexed as

Protein Sorting SignalsProtein Translocation SystemsEscherichia coliMolecular ChaperonesProteinsProtein TransportSEC Translocation ChannelsYeastsMolecular ChaperonesProteinsProtein Sorting SignalsProtein Translocation SystemsSEC Translocation ChannelsChaperonesEnergeticsInsertasesProtein targetingTranslocase

Identifiers

PMID31187382
OpenAlexW2951299699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.