Evidence map›Paper›PMID 31187344›Full record

Trial reportJournal of general internal medicine2019

Interventions to Reduce Unhealthy Alcohol Use among Primary Care Patients with HIV: the Health and Motivation Randomized Clinical Trial.

Derek D Satre, Amy S Leibowitz, Wendy Leyden, Sheryl L Catz, C Bradley Hare, Hannah Jang, Jennifer O Lam, Kendall J Bryant, Constance M Weisner, Stacy A Sterling and 3 more

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of general internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01671501 (Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01671501 nacompletednot on this map

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

TypeinterventionalSponsorUniversity of California, San FranciscoRan2013 to 2017Enrolled614ConditionsHIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic IntoxicationArmsMotivational Interviewing, Email Feedback, Usual Care
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Derek D SatreDepartment of Psychiatry, Weill Institute for Neurosciences, University of California, Box 0984, San Francisco, 401 Parnassus Avenue, San Francisco, CA, 94143, USA. derek.satre@ucsf.edu.
Amy S LeibowitzDivision of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA, 94612, USA.
Wendy LeydenDivision of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA, 94612, USA.
Sheryl L CatzBetty Irene Moore School of Nursing, University of California, Davis, 2450 48th Street, Suite 2600, Sacramento, CA, 95817, USA.
C Bradley HareKaiser Permanente San Francisco Medical Center, 2238 Geary Blvd, San Francisco, CA, 94115, USA.
Hannah JangDivision of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA, 94612, USA.
Jennifer O LamDivision of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA, 94612, USA.
Kendall J BryantNational Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
Constance M WeisnerDepartment of Psychiatry, Weill Institute for Neurosciences, University of California, Box 0984, San Francisco, 401 Parnassus Avenue, San Francisco, CA, 94143, USA.
Stacy A SterlingDivision of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA, 94612, USA.
Michael HorbergMid-Atlantic Permanente Research Institute, Kaiser Permanente Mid-Atlantic States, 2101 East Jefferson, Rockville, MD, 20852, USA.
Paul VolberdingAIDS Research Institute, University of California, San Francisco, CA, 94158, USA.
Michael J SilverbergDivision of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA, 94612, USA.
Kaiser Permanente · USUniversity of California, San Francisco · USKaiser Permanente San Francisco Medical Center · USNational Institute on Alcohol Abuse and Alcoholism · USUniversity of California, Davis · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Mentoring alcohol use intervention research in HIV health care settingsK24AA025703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Derek D Satre · 2018 to 2026
$1.8M
Population-based Screening and Brief Intervention in Primary Care: Health and Drinking Outcomes, Cost and UtilizationR01AA025902 · NIAAA · KAISER FOUNDATION RESEARCH INSTITUTE · PI STERLING, STACY ANN · 2017 to 2020
$1.6M
NIAAA NIH HHS K24 AA025703NIAAA NIH HHS R01 AA025902NIAID NIH HHS P30 AI027763
6 · The paper itself

Abstract

backgroundUnhealthy alcohol use has adverse effects on HIV treatment. Screening, brief intervention, and referral to treatment (SBIRT) has some evidence of efficacy but may not be sufficient for those with low motivation or comorbid substance use.

objectiveTo examine the effectiveness of motivational interviewing (MI) and emailed feedback (EF) among primary care HIV-positive patients, compared with treatment as usual care (UC) only, which included SBIRT.

designRandomized clinical trial.

participantsSix hundred fourteen adult HIV-positive patients in Kaiser Permanente Northern California who reported prior-year unhealthy alcohol use.

interventionParticipants were randomized to either three sessions of MI (one in person and two by phone), information regarding alcohol risks via EF through a patient portal, or UC alone. MI and EF participants who reported unhealthy alcohol use at 6 months were offered additional MI and EF treatment, respectively. MAIN MEASURES: Participant-reported unhealthy alcohol use (defined as ≥ 4/≥ 5 drinks per day for women/men), alcohol problems at 12 months, based on blinded telephone interviews. Secondary outcomes included drug use and antiretroviral (ART) adherence. KEY

resultsAt 12 months, there were no overall group differences, but in all three arms, there were declines in unhealthy alcohol use and alcohol-related problems (p < 0.001). Participants reporting low motivation to reduce drinking at baseline were less likely to report unhealthy alcohol use if they received MI vs. EF and UC (p = 0.013). At 6 months, reported illegal drug use/misuse of prescription drugs other than marijuana was lower in the MI arm than EF or UC (p = 0.012). There were no differences in ART adherence between groups.

conclusionsIn a randomized trial of HIV-positive patients using two behavioral interventions compared with SBIRT alone, participants in all three conditions reduced unhealthy alcohol use. MI may provide added benefit for patients with low motivation or who report illegal drug use/misuse of prescription drugs.

trial registrationNCT01671501 ( ClinicalTrials.gov ).

Indexed as

Text MessagingAdultAlcohol DrinkingAlcoholismFemaleHIV InfectionsHumansMaleMiddle AgedMotivational InterviewingPrimary Health Careadaptive interventionalcoholdigital healthHIVmotivational interviewingprimary careSBIRT

Identifiers

PMID31187344
PMCPMC6816606
OpenAlexW2953240215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.