ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2019
Portraying infective endocarditis: results of multinational ID-IRI study.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- A comparison of different antibiotic regimens for the treatment of infective endocarditis.The Cochrane database of systematic reviews · 2020Pooled it
- Altered Mental Status in Emergency Department Patient with Cerebral Septic Emboli from Infective Endocarditis: Case Report.Clinical practice and cases in emergency medicine · 2026Article
- Data-driven phenotyping of infective endocarditis using unsupervised machine learning: toward a personalized approach.BMC infectious diseases · 2026Article
- Contemporary Overview of Aortic Regurgitation in Young Individuals: Insights From Real-Life Evidence.Journal of the American Heart Association · 2026Review
- Infective Endocarditis in a Tertiary Hospital in Porto-Is There Anything New?Infectious disease reports · 2025Article
- Article
- Non-β-hemolytic Streptococcal Bacteremia in Patients With Heart Valve Prosthesis-Is It Always Infective Endocarditis?Open forum infectious diseases · 2025Article
- Mortality Associated with Surgical Site Infections Following Cardiac Surgery: Insights from the International ID-IRI Study.IJID regions · 2025Article
- Accelerated Apixaban Removal by Using the ADVanced Organ Support (ADVOS) Albumin Hemodialysis System-A Case Report.The Thoracic and cardiovascular surgeon reports · 2025Article
- Infective Endocarditis With Coronary Artery Embolization and Multisystem Involvement in a Patient With a History of IV Drug Use: A Case Report.Journal of community hospital internal medicine perspectives · 2025Article
- Complicated infective endocarditis of the bioprosthetic mitral valve following the transcatheter mitral valve-in-valve procedure: a case report and literature review.European heart journal. Case reports · 2025Article
- Infective endocarditis in a Finnish tertiary care hospital: from etiology to embolic events.Annals of medicine · 2024Article
- Clinical profile, microbiology and outcomes in infective endocarditis treated with aortic valve replacement: a multicenter case-control study.BMC infectious diseases · 2024Article
- Atypical Infective Endocarditis Presenting With Euthermia and Right Lower Quadrant Abdominal Pain.Cureus · 2024Article
- Epidemiological and microbial trends of infective endocarditis in western Norway: a 7-year prospective observational study.BMC infectious diseases · 2024Observational
- Prospective Clinical Follow-Up Results of Infective Endocarditis.Infectious diseases & clinical microbiology · 2024Article
- Rothia dentocariosa endocarditis with brain abscess and splenic abscess: case report and brief review.Frontiers in cardiovascular medicine · 2024Article
- Infectious causes of fever of unknown origin in developing countries: An international ID-IRI study.Journal of intensive medicine · 2024Article
- Perioperative Complications in Infective Endocarditis.Journal of clinical medicine · 2023Review
- Streptococcal infective endocarditis: clinical features and outcomes according to species.Infection · 2023Article
Corrections and comments
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Authors and funding
61 authors at 20 institutions in 14 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infective endocarditis is a growing problem with many shifts due to ever-increasing comorbid illnesses, invasive procedures, and increase in the elderly. We performed this multinational study to depict definite infective endocarditis. Adult patients with definite endocarditis hospitalized between January 1, 2015, and October 1, 2018, were included from 41 hospitals in 13 countries. We included microbiological features, types and severity of the disease, complications, but excluded therapeutic parameters. A total of 867 patients were included. A total of 631 (72.8%) patients had native valve endocarditis (NVE), 214 (24.7%) patients had prosthetic valve endocarditis (PVE), 21 (2.4%) patients had pacemaker lead endocarditis, and 1 patient had catheter port endocarditis. Eighteen percent of NVE patients were hospital-acquired. PVE patients were classified as early-onset in 24.9%. A total of 385 (44.4%) patients had major embolic events, most frequently to the brain (n = 227, 26.3%). Blood cultures yielded pathogens in 766 (88.4%). In 101 (11.6%) patients, blood cultures were negative. Molecular testing of vegetations disclosed pathogens in 65 cases. Overall, 795 (91.7%) endocarditis patients had any identified pathogen. Leading pathogens (Staphylococcus aureus (n = 267, 33.6%), Streptococcus viridans (n = 149, 18.7%), enterococci (n = 128, 16.1%), coagulase-negative staphylococci (n = 92, 11.6%)) displayed substantial resistance profiles. A total of 132 (15.2%) patients had cardiac abscesses; 693 (79.9%) patients had left-sided endocarditis. Aortic (n = 394, 45.4%) and mitral valves (n = 369, 42.5%) were most frequently involved. Mortality was more common in PVE than NVE (NVE (n = 101, 16%), PVE (n = 49, 22.9%), p = 0.042).
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