ArticleEuropean journal of applied physiology2019
Leg- vs arm-cycling repeated sprints with blood flow restriction and systemic hypoxia.
Article in European journal of applied physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Acute and Chronic Effects of Blood Flow Restricted High-Intensity Interval Training: A Systematic Review.Sports medicine - open · 2022Pooled it
- Effects of high intensity interval exercise on cerebrovascular function: A systematic review.PloS one · 2020Pooled it
- Blood Flow Restriction Does Not Impair Single, All-Out Sprint Cycling Performance.European journal of sport science · 2026Trial
- Dose-response effects of caffeine during repeated cycling sprints in normobaric hypoxia to exhaustion.European journal of applied physiology · 2025Trial
- Continuous blood flow restriction during repeated-sprint exercise increases peripheral but not systemic physiological and perceptual demands.European journal of sport science · 2024Trial
- Benefits of 6-weeks high-intensity circuit training with or without blood flow restriction on physical fitness in active males: A randomized controlled trial.Journal of exercise science and fitness · 2026Article
- Integrating mechanical, physiological, and muscle oxygenation responses during field-based tethered repeated-sprint exercise in male professional soccer players.Physiological reports · 2026Article
- Blood flow restriction induces similar peripheral stress but greater central drive impairments than systemic hypoxia during repeated cycling sprints.European journal of applied physiology · 2026Article
- Effects of High-Intensity Interval Training with Blood Flow Restriction Versus Normobaric Hypoxia on Physiological Parameters in Apparently Healthy Young Men.Sports (Basel, Switzerland) · 2026Article
- Acute effects of upper-limb blood flow restriction training on dual-task postural control and physiological correlates in older adults.Journal of neuroengineering and rehabilitation · 2026Article
- Effects of blood flow restriction interval training on aerobic, anaerobic capacity, and muscle strength in healthy adults: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Muscle deoxygenation responses are similar between repeated sprints in hypoxia performed with uni- versus bi-lateral knee extensions but reduced compared to cycling.European journal of sport science · 2025Article
- Effects of BFR-RST on upper limb performance in boxers: a study based on physiological indices, anthropometric measurement indices, anaerobic power, and punching performance.Frontiers in physiology · 2025Article
- Cardiorespiratory and muscle oxygenation responses to voluntary hypoventilation at low lung volume in upper body repeated sprints.European journal of applied physiology · 2024Article
- The Discrepancy Between External and Internal Load/Intensity during Blood Flow Restriction Exercise: Understanding Blood Flow Restriction Pressure as Modulating Factor.Sports medicine - open · 2024Article
- Impact of systemic hypoxia and blood flow restriction on mechanical, cardiorespiratory, and neuromuscular responses to a multiple-set repeated sprint exercise.Frontiers in physiology · 2024Article
- Application of blood flow restriction in hypoxic environment augments muscle deoxygenation without compromising repeated sprint exercise performance.Experimental physiology · 2023Article
- Acute physiological responses to steady-state arm cycling ergometry with and without blood flow restriction.European journal of applied physiology · 2023Article
- Article
- Augmented muscle deoxygenation during repeated sprint exercise with post-exercise blood flow restriction.Physiological reports · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim was to compare changes in peripheral and cerebral oxygenation, as well as metabolic and performance responses during conditions of blood flow restriction (BFR, bilateral vascular occlusion at 0% vs. 45% of resting pulse elimination pressure) and systemic hypoxia (~ 400 m, F
methodsSeven participants (26.6 ± 2.9 years old; 74.0 ± 13.1 kg; 1.76 ± 0.09 m) performed four sessions of RST (10-s maximal sprints with 20-s recovery until exhaustion) during both leg and arm cycling to measure power output and metabolic equivalents as well as oxygenation (near-infrared spectroscopy) of the muscle tissue and prefrontal cortex.
resultsMean power output was lower in arms than legs (316 ± 118 vs. 543 ± 127 W; p < 0.001) and there were no differences between conditions for a given limb. Arms demonstrated greater changes in concentration of deoxyhemoglobin (∆[HHb], - 9.1 ± 6.1 vs. - 6.5 ± 5.6 μm) and total hemoglobin concentration (∆[tHb], 15.0 ± 10.8 vs. 11.9 ± 7.9 μm), as well as the absolute maximum tissue saturation index (TSI, 62.0 ± 8.3 vs. 59.3 ± 8.1%) than legs, respectively (p < 0.001), demonstrating a greater capacity for oxygen extraction. Further, there were greater changes in tissue blood volume [tHb] during BFR only compared to all other conditions (p < 0.01 for all).
conclusionsThe combination of BFR and/or hypoxia led to increased changes in [HHb] and [tHb] likely due to greater vascular resistance, to which arms were more responsive than legs.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.