Observational studySurgical endoscopy2020
Endoscopic full-thickness resection of gastric subepithelial tumors with the gFTRD-system: a prospective pilot study (RESET trial).
Observational study in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Endoscopic Full-thickness Resection of Gastric Subepithelial Tumors With the gFTRD
Gastroduodenal Full Thickness Resection Device Registry - gdFTRD® Registry
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Endoscopic full-thickness resection for upper gastrointestinal tract lesions: a systematic review and meta-analysis.Surgical endoscopy · 2023Pooled it
- Efficacy and Safety of Full-thickness Resection Device (FTRD) for Colorectal Lesions Endoscopic Full-thickness Resection: A Systematic Review and Meta-Analysis.Journal of clinical gastroenterology · 2021Pooled it
- Methods for Endoscopic Removal of Over-the-Scope Clip: A Systematic Review.Canadian journal of gastroenterology & hepatology · 2020Pooled it
- Patient-Reported-Outcome-Measures (PROMs) After Gastrointestinal Endoscopic Resections.United European gastroenterology journal · 2026Trial
- Comparison of ligation-assisted versus snare traction-assisted endoscopic full-thickness resection for small (≤ 1.5 cm) gastric submucosal tumors originating from the muscularis propria: a propensity score-matched analysis.Surgical endoscopy · 2026Article
- Endoscopic full-thickness resection of upper gastrointestinal tract: a review on closure techniques.Clinical endoscopy · 2026Review
- Expanded options for removal of an old over-the-scope clip.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- Comparison Between the Efficacy of EFR and CASL in the Treatment of Small Gastric Stromal Tumors: A Retrospective Study.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Article
- Endoloop-assisted endoscopic removal of over-the-scope and full-thickness resection device clips: Prospective study.Endoscopy international open · 2026Article
- Preset pursestring procedure: Innovative auxiliary method of endoscopic full-thickness resection in small gastric stromal tumors.Endoscopy international open · 2026Article
- Comparison of endoscopic resection, laparoscopic resection, and laparoscopic endoscopic cooperative surgery in esophageal or gastric subepithelial lesions in a Thai medical school.Asian biomedicine : research, reviews and news · 2025Article
- Endoscopic Full Thickness Resection Device (FTRDDiagnostics (Basel, Switzerland) · 2025Review
- Advancements in Endoscopic Treatment for Gastric Subepithelial Tumors.Gut and liver · 2025Review
- Clinical safety of a novel over-the-scope gastroduodenal full-thickness resection device for the treatment of upper GI tract lesions: a multicenter experience.iGIE : innovation, investigation and insights · 2024Article
- Gastric Glomus Tumor Resected by Submucosal Tunneling Endoscopic Resection.ACG case reports journal · 2024Article
- Efficacy and safety of endoscopic subserosal dissection treatment for gastrointetinal submucosal tumors in the upper gastrointestinal tract.BMC surgery · 2024Article
- Modern Management of Gastric Neuroendocrine Neoplasms.Current treatment options in oncology · 2024Review
- Endoscopic resection of gastric gastrointestinal stromal tumor using clip-and-cut endoscopic full-thickness resection: a single-center, retrospective cohort in Korea.Clinical endoscopy · 2024Article
- The Role of Specialized Instruments for Advanced Endoscopic Resections in Gastrointestinal Disease.Life (Basel, Switzerland) · 2023Article
- Therapeutic Challenges for Gastric Neuroendocrine Neoplasms: Take It or Leave It?Medicina (Kaunas, Lithuania) · 2023Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastric subepithelial tumors (SET) are rare and usually benign. However, up to 13% are malignant. Histology after conventional biopsy often is inconclusive. Surveillance endoscopies are the consequence in the majority of gastric SET cases. For SET arising from deeper layers endoscopic resection (ER) with the standard techniques is difficult and associated with the risk of perforation. The RESET trial further evaluates feasibility, efficacy and safety of clip-assisted endoscopic full-thickness resection (EFTR) for gastric SET using the novel gastric full-thickness-resection device (gFTRD). MATERIALS AND
methodsThe RESET trial was initiated in March 2017 (NCT03096236) and designed as prospective observational multicenter pilot trial. Gastric SET up to 15 mm were included. Primary endpoint was technical success (complete enbloc resection). Secondary endpoints were R0 resection, full-thickness resection, adverse events and recurrency at 3-months follow-up. For resection we used the gFTRD (Ovesco Endoscopy, Tübingen, Germany).
results29 patients underwent gastric EFTR. Histology prior EFTR after conventional biopsy could define histological tumor type in only 31.2%. Primary endpoint was reached in 89.7%. Histology of the full-thickness-resection specimen could define histological tumor type in 100%. 76% of all SET could be resected histologically complete (R0) and a full-thickness-resection specimen could be obtained in 65.5%. In 31% periprocedural minor bleeding was observed and managed endoscopically. Follow-up was available in 79.3% (OTSC detachment in 78.3%, OTSC in position in 21.7%). No signs of residual or recurrent tumors were observed after 3 months.
conclusionEFTR of gastric SET with gFTRD is feasible and safe. EFTR allows a definite histological diagnosis (including sufficient risk stratification in case of GIST or NET) in contrast to conventional biopsy. R0-resection is possible in most cases and might obviate the need for further surveillance endoscopies for selected patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.