Evidence map›Paper›PMID 31187212›Full record

ArticleMikrochimica acta2019

A semi-quantitative rapid multi-range gradient lateral flow immunoassay for procalcitonin.

Kseniya V Serebrennikova, Jeanne V Samsonova, Alexander P Osipov

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Low-cost, point-of-care biomarker quantification.Current opinion in biotechnology · 2022
    Review
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kseniya V SerebrennikovaChemistry Faculty, Lomonosov Moscow State University, Moscow, Leninskiye Gory, 119991, Russia. ksenijasereb@mail.ru.
Jeanne V SamsonovaChemistry Faculty, Lomonosov Moscow State University, Moscow, Leninskiye Gory, 119991, Russia.
Alexander P OsipovChemistry Faculty, Lomonosov Moscow State University, Moscow, Leninskiye Gory, 119991, Russia.
National University of Science and Technology · RULomonosov Moscow State University · RU

Funding

Ministry of Education and Science of the Russian Federation 16.6548.2017/BY
6 · The paper itself

Abstract

A rapid semi-quantitative gradient lateral flow immunoassay (LFIA) of procalcitonin (PCT), a peptide precursor of the hormone calcitonin, was developed. The method is based on particular analyte cut-offs by immobilizing specific antibodies on the test strip with a consistent (gradient) increase in concentration from line to line. Semi-quantitative multi-range analysis is evaluated visually by counting the number of colored test lines corresponding to a certain concentration range of sepsis marker: [PCT]˂0.25; 0.25 ≤ [PCT] < 0.5; 0.5 ≤ [PCT] < 2; 2 ≤ [PCT] < 10; [PCT] ≥ 10 ng·mL

Indexed as

Antibodies, ImmobilizedAntibodies, MonoclonalBiomarkersHumansImmunoassayProcalcitoninSepsisAntibodies, ImmobilizedAntibodies, MonoclonalBiomarkersProcalcitoninBarcodeCut-off adjustmentDiagnostic cut-offsGold nanopopcornsGold nanospheresImmunochromatographySepsis markerTest strip

Identifiers

PMID31187212
OpenAlexW2952867885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.