Evidence map›Paper›PMID 31187080›Full record

ReviewJournal of the Endocrine Society2019

Reprogramming Cells to Make Insulin.

Wendy M McKimpson, Domenico Accili

Open access · goldAbstract readReview
In one paragraph

Review in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wendy M McKimpsonDepartment of Medicine (Endocrinology), Columbia University, New York, New York.ORCID 0000-0002-2262-5998
Domenico AcciliDepartment of Medicine (Endocrinology), Columbia University, New York, New York.
Columbia University · US

Funding

POSTDOCTORAL TRAINING IN ARTERIOSCLEROSIS RESEARCHT32HL007343 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENRY N GINSBERG, Muredach P Reilly · 1985 to 2026
$12.7M
ROLE OF FORKHEAD PROTEINS IN INSULIN ACTIONR01DK057539 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ACCILI, DOMENICO · 2001 to 2024
$10.7M
MECHANISMS OF BETA CELL FAILURER01DK064819 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ACCILI, DOMENICO · 2003 to 2025
$10.5M
MOUSE MODELS OF INSULIN RESISTANCER01DK058282 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ACCILI, DOMENICO · 2000 to 2023
$6.2M
MOUSE MODELS OF INSULIN RESISTANCER37DK058282 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ACCILI, DOMENICO · 2010 to 2019
$4.4M
NHLBI NIH HHS T32 HL007343NIDDK NIH HHS R01 DK057539NIDDK NIH HHS R01 DK064819NIDDK NIH HHS R37 DK058282
6 · The paper itself

Abstract

Type 1 diabetes is a disease characterized by the destruction of insulin-secreting

Indexed as

cell plasticityenteroendocrine cellgut endocrine systempancreatic β-cellstem cell differentiation

Identifiers

PMID31187080
PMCPMC6546342
OpenAlexW2941980397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.