Evidence map›Paper›PMID 31187078›Full record

ArticleJournal of the Endocrine Society2019

Pancreatic Neuroendocrine Tumor in a Young Child With Tuberous Sclerosis Complex 1.

Shilpa Mehta, Larisa Rusyn, Howard Ginsburg, Cristina Hajdu, Brenda Kohn

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shilpa MehtaDivision of Pediatric Endocrinology and Diabetes, Department of Pediatrics, New York University School of Medicine, Hassenfeld Children's Hospital at NYU Langone, New York, New York.ORCID 0000-0002-4494-5861
Larisa RusynDivision of Pediatric Endocrinology and Diabetes, Department of Pediatrics, New York University School of Medicine, Hassenfeld Children's Hospital at NYU Langone, New York, New York.
Howard GinsburgDivision of Pediatric Surgery, Department of Surgery, New York University School of Medicine, Hassenfeld Children's Hospital at NYU Langone, New York, New York.
Cristina HajduDepartment of Pathology, New York University School of Medicine, New York, New York.
Brenda KohnDivision of Pediatric Endocrinology and Diabetes, Department of Pediatrics, New York University School of Medicine, Hassenfeld Children's Hospital at NYU Langone, New York, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic neuroendocrine tumors (PNETs) occur in the context of tuberous sclerosis complex (TSC). To date, PNETs in association with TSC have been described almost exclusively in adults and in the context of TSC2. We present the evaluation of a PNET in a young child with TSC1. A 3-year, 6-month-old boy with TSC1 was found on surveillance to have a small pancreatic lesion measuring 0.4 cm on magnetic resonance imaging (MRI). The lesion showed interval enlargement to 1 cm on serial MRI studies during the ensuing 16 weeks. Endocrine laboratory tests did not reveal a functional tumor. The patient underwent enucleation of the pancreatic lesion. Microscopic examination defined a well-differentiated PNET, grade II/intermediate grade with a mitotic rate of two mitotic figures per 10 high-powered field and Ki-67 proliferation index of ∼15%. The tumor was positive for the

Indexed as

pancreatic neuroendocrine tumortuberous sclerosis complex

Identifiers

PMID31187078
PMCPMC6546344

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.