ArticleOncology letters2019
Tumor suppressor function of miR-129-5p in lung cancer.
Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- The Promise and Pursuit of MicroRNAs for Cancer Treatment.Biomolecules · 2026Review
- Circ_103128 is associated with the tumorigenesis of medulloblastoma.Journal of cancer research and clinical oncology · 2023Article
- Development of a 5-FU modified miR-129 mimic as a therapeutic for non-small cell lung cancer.Molecular therapy oncolytics · 2023Article
- The Role of the Selected miRNAs as Diagnostic, Predictive and Prognostic Markers in Non-Small-Cell Lung Cancer.Journal of personalized medicine · 2022Review
- Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells.International journal of molecular sciences · 2022Article
- Exosomes derived from microRNA-129-5p-modified tumor cells selectively enhanced suppressive effect in malignant behaviors of homologous colon cancer cells.Bioengineered · 2021Article
- Role of microRNA-129 in cancer and non-cancerous diseases (Review).Experimental and therapeutic medicine · 2021Review
- Article
- Overexpression of microRNA-129-5p in glioblastoma inhibits cell proliferation, migration, and colony-forming ability by targeting ZFP36L1.Bosnian journal of basic medical sciences · 2020Article
- MiR-129-5p alleviates myocardial injury by targeting suppressor of cytokine signaling 2 after ischemia/reperfusion.The Kaohsiung journal of medical sciences · 2020Article
- MicroRNA and ROS Crosstalk in Cardiac and Pulmonary Diseases.International journal of molecular sciences · 2020Review
- Long noncoding RNA LINC00314 facilitates osteogenic differentiation of adipose-derived stem cells through the hsa-miR-129-5p/GRM5 axis via the Wnt signaling pathway.Stem cell research & therapy · 2020Article
- MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-κB pathway.Bioscience reports · 2020Article
- MicroRNA-129-2-3p directly targets Wip1 to suppress the proliferation and invasion of intrahepatic cholangiocarcinoma.Journal of Cancer · 2020Article
- LINC00501 Inhibits the Growth and Metastasis of Lung Cancer by Mediating miR-129-5p/HMGB1.OncoTargets and therapy · 2020Article
- MiR-519a functions as a tumor suppressor and is negatively associated with poor prognosis of non-small cell lung cancer.Cancer biomarkers : section A of Disease markers · 2020Article
- miR-129-5p Inhibits Bone Formation Through TCF4.Frontiers in cell and developmental biology · 2020Article
- miR-129-5p improves cardiac function in rats with chronic heart failure through targeting HMGB1.Mammalian genome : official journal of the International Mammalian Genome Society · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lung cancer causes severe health problems worldwide and, in China, besides being the principal cause of mortality among urbanites, it is the second leading cause of mortality in the rural population, preceded by hepatocellular carcinoma. Between 80 and 85% of lung cancer is classified as non-small cell lung cancer (NSCLC). The high mobility group box 1 (HMGB1) protein serves an important function in the tumor microenvironment and antitumor response, and may be targeted by microRNA (miR). In the present study, miR-129-5p was identified to target HMGB1 and miR-129-5p exhibited low expression levels in NSCLC tissues. Overexpression of miR-129-5p inhibited cell proliferation and promoted cell apoptosis. In conclusion, the results of the present study suggested the inhibitory function of miR-129-5p and revealed a novel therapeutic target for further investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.