Evidence map›Paper›PMID 31186528›Full record

ArticleModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc2019

Characterization of spatial distribution of tumor-infiltrating CD8

Yohei Masugi, Tokiya Abe, Akihisa Ueno, Yoko Fujii-Nishimura, Hidenori Ojima, Yutaka Endo, Yusuke Fujita, Minoru Kitago, Masahiro Shinoda, Yuko Kitagawa and 1 more

Open access · bronzeAbstract read
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In one paragraph

Article in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. CD8Cancer science · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Panoramic tumor microenvironment in pancreatic ductal adenocarcinoma.Cellular oncology (Dordrecht, Netherlands) · 2024
    Review
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yohei MasugiDepartment of Pathology, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0002-6952-4043
Tokiya AbeDepartment of Pathology, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0003-0665-8834
Akihisa UenoDepartment of Pathology, Keio University School of Medicine, Tokyo, Japan.
Yoko Fujii-NishimuraDepartment of Pathology, Keio University School of Medicine, Tokyo, Japan.
Hidenori OjimaDepartment of Pathology, Keio University School of Medicine, Tokyo, Japan.
Yutaka EndoDepartment of Pathology, Keio University School of Medicine, Tokyo, Japan.
Yusuke FujitaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
Minoru KitagoDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
Masahiro ShinodaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
Yuko KitagawaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
Michiie SakamotoDepartment of Pathology, Keio University School of Medicine, Tokyo, Japan. msakamot@z5.keio.jp.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The abundance of cytotoxic T-cell infiltrates has important implications for patient outcome and therapeutic design for pancreatic ductal adenocarcinoma. However, intratumoral heterogeneity remains a challenge to understanding the complex immune microenvironment. We hypothesized that characterizing CD8

Indexed as

Tumor MicroenvironmentAdenocarcinomaAgedCD8-Positive T-LymphocytesFemaleHumansImmunohistochemistryLymphocytes, Tumor-InfiltratingMaleMiddle AgedPancreatic NeoplasmsPrognosisSurvival Rate

Identifiers

PMID31186528
OpenAlexW2952001837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.