Evidence map›Paper›PMID 31186493›Full record

ArticleLeukemia2019

Clonal hematopoiesis by SLIT1-mutated hematopoietic stem cells due to a breakdown of the autocrine loop involving Slit1 in acquired aplastic anemia.

Kohei Hosokawa, Hiroki Mizumaki, Mahmoud I Elbadry, Chizuru Saito, J Luis Espinoza, An Thi Thanh Dao, Takamasa Katagiri, Ai Harashima, Akihiro Kikuchi, Akinori Kanai and 5 more

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Kohei Hosokawa *Department of Hematology & Respirology, Kanazawa University, Kanazawa, Japan.
Hiroki Mizumaki *Department of Hematology & Respirology, Kanazawa University, Kanazawa, Japan.
Mahmoud I ElbadryDepartment of Hematology & Respirology, Kanazawa University, Kanazawa, Japan.
Chizuru SaitoDepartment of Hematology & Respirology, Kanazawa University, Kanazawa, Japan.
J Luis EspinozaDepartment of Hematology & Respirology, Kanazawa University, Kanazawa, Japan.
An Thi Thanh DaoDepartment of Hematology & Respirology, Kanazawa University, Kanazawa, Japan.
Takamasa KatagiriDepartment of Clinical Laboratory Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Ai HarashimaDepartment of Biochemistry, Kanazawa University, Kanazawa, Japan.
Akihiro KikuchiDepartment of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
Akinori KanaiResearch Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Hirotaka MatsuiResearch Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Toshiya InabaResearch Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Masafumi TaniwakiDepartment of Hematology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yasuhiko YamamotoDepartment of Biochemistry, Kanazawa University, Kanazawa, Japan.
Shinji NakaoDepartment of Hematology & Respirology, Kanazawa University, Kanazawa, Japan. snakao8205@staff.kanazawa-u.ac.jp.
Kanazawa University · JPHiroshima University · JPKyoto Prefectural University of Medicine · JPNational Institute for Physiological Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HematopoiesisAnemia, AplasticBone Marrow CellsCell ProliferationChromosome AberrationsChromosomes, Human, Pair 13CytokinesExomeHematopoietic Stem CellsHumansInflammationIn Situ Hybridization, FluorescenceK562 CellsMutationNerve Tissue ProteinsPhenotypeCytokinesNerve Tissue ProteinsReceptors, ImmunologicRoundabout ProteinsSLIT1 protein, humanSTAT3 protein, humanSTAT3 Transcription Factor

Identifiers

PMID31186493
OpenAlexW2949600487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.